Objective: To to investigate the effects of virtual reality assisted upper limb robot training on cognitive function recovery of stroke patients.Methods: 60 stroke patients(final test in 49 cases,23 cases in the experimental group and26 cases in the control group)were selected,who were admitted to the department of rehabilitation medicine and department of neurology of Pingshan district traditional Chinese medicine hospital in Shenzhen from December 2018 to June 2019 and met the inclusion criteria.Both groups received the same basic treatment.The control group was given conventional cognitive training,while the experimental group was given upper-limb robot training assisted by virtual reality.Patients in both groups were treated for eight weeks(30minutes six times a week).Both groups were evaluated for motor function and Cognitive function before and after 8 weeks of treatment,including MoCoA(Motreal Cognitive Assessment)rating scale,modified Barthel index(MBI),upper limb part of fugl-meyer rating scale(fma-ue),and event-related potential P300.Results: 1.After 8 weeks of treatment,the scores of FMA-UE in both groups was increased significantly in comparison to that before treatment,with very significant difference(P < 0.01).the score of experimental group is higher than the control group,with significant difference(P < 0.05).The upper limb scores of two groups were increased in comparison to that before treatment,with very significant difference(P < 0.01),and the upper limb scores of experimental group is better than that of control group,with very significant difference(P <0.01).The wrist score of the two groups increased compared with that before treatment,and the difference within the group was significant(P<0.05),but there is no significant difference between the experimental group and the control group(P>0.05).2.After 8 weeks of treatment,the score of improved Barthel index in both the experimental group and the control group was significantly higher than that before treatment(P<0.01),but there was no significant difference between the groups(P>0.05).3.After 8 weeks of treatment,it was found that the scores of visual space,executive function,attention,orientation and total MoCA in the experimental group were significantly higher than those before treatment with very significant difference(P<0.01),and the scores of delayed memory were higher than those before treatment with significant difference(P<0.05).The attention score and MoCA total score of patients in the control group were significantly higher than those before treatment,with very significant difference(P<0.01),and the scores of two sub-items of MoCA,including visual space,executive function and directional force,were higher than those before treatment with significant difference(P<0.05).The comparison between groups showed that after treatment,the scores of three sub-items of MoCA,including visual space,executive function,attention and direction,were higher in the experimental group than in the control group with significant difference(P<0.05).Among them,there was no significant difference in the score of delayed memory before and after treatment(P>0.05),and there was significant difference in the total MoCA scores between the two groups(P<0.05).4.After 8 weeks of treatment,the incubation period of P300 in the two groups was shorter than that before treatment,and the difference was very significant(P<0.01).The amplitude of P300 was higher than that before treatment,and the difference in the control group was significant(P<0.05),while the difference in the experimental group was very significant(P<0.01).The comparison between groups showed that the incubation period of patients in the experimental group was shorter than that in the control group after treatment,and the difference was very significant(P<0.01).After treatment,the amplitude of the experimental group increased compared with the control group,and the difference was significant(P<0.05).5.Correlation analysis of the improvement of cognitive function and upper limb function after treatment in the two groups: in the experimental group,the improvement of cognitive function was positively correlated with the improvement of upper limb function in patients using the upper limb rehabilitation robot(r=0.44,P=0.04).In the control group,the improvement of cognitive function was not significantly correlated with the improvement of upper limb function(r=0.07,P=0.74).Conclusion: 1.The upper-limb robot training assisted by virtual reality can improve not only hemiplegic side upper limb movement function but also cognitive function of patients with stroke in the experimental group.3.When comparing the two groups,the effect of upper limb robot training assisted by virtual reality on motor function of the upper limbs and cognitive function of stroke patients in the experimental group was better than that of cognitivetraining in the control group.3.There is a positive correlation between the improvement of cognitive function and the improvement of upper limb motor function in the experimental group. |