Study On The Correlation Between Red Blood Cell Distribution Width And Renal Function In Patients With Primary Glomerular Disease

Objective: To explore the correlation between the red blood cell distribution width(RDW)and the renal function in patients with primary glomerular disease.Methods: This study involved 194 primary glomerular disease patients from our hospital.This was a retrospective study.General clinical data and laboratory test results were collected from these patients to analyze the relationship between RDW and renal function.Results: Among the 194 cases of patients with primary glomerular disease,the mean age was 41.20�14.11 years,male: female= 1.18:1.According to the RDW quartile at admission,patients were divided into four groups(?12.50% ?12.50%-12.955%?12.955%-13.71%??13.71%).One-way ANOVA showed the mean values of age,systolic blood pressure,mean arterial pressure,erythrocyte number,hemoglobin,erythrocyte sedimentation rate,serum albumin,24-hour urinary protein,urea,serum cystatin C,lactate dehydrogenase and lipoprotein a were different,and the difference was statistically significant(P < 0.05).Pearson linear correlation analysis showed that RDW was positively correlated with age,erythrocyte number,white blood cell number,percentage of monocytes,erythrocyte sedimentation rate,24-hour urinary protein,urea,serum creatinine,cystatin C,lactate dehydrogenase(P < 0.05),and negatively correlated with hemoglobin,estimated glomerular filtration rate and serum albumin(P < 0.05).Conclusion: Red blood cell distribution width is negatively correlated with estimated glomerular filtration rate and serum albumin level,and positively correlated with age and 24-hour urinary protein,serum creatinine,urea,cystatin C and lactate dehydrogenase level in patients with primary glomerular disease.