| Objective: Optical coherence tomography was used to observe the changes of retinal microstructures in patients with local choroidal depression..Methods:Retrospective case study.A total of 36 patients with 40 lesions in 38 FCE eyes who were diagnosed by spectral-domain optical coherence tomography in the second hospital of hebei medical university from 2011 to 2020 were included in the study.According to the presence or absence of RPE complications,the patients were divided into two groups,namely,the FCE group and the FCE complication group.Then,according to the type of complications,the FCE complication group was subdivided into two subgroups,namely,the CNV group(with choroidal neovascularization)and the other complication group(with macular anterior membrane with retinal splitting,macular anterior membrane,pigment meningitis,macular hole,and central serous choroidal retinopathy).Heidelberg optical coherence tomography(OCT)was used to measure the width,depth and position of the lesion.The FCE group was compared with the FCE complication group,the CNV group and other complications group,and the clinical and OCT characteristics of each group were compared,and the risk factors for the occurrence of related complications in the localized choroidal depression were further summarized and analyzed.Results:1.A total of 36 patients with 40 lesions in 38 eyes were enrolled.The average age of the patients was 48.92±15.10 years.There were 34 cases of monocular disease(94%).Among all the lesions,31(77.5%)were compact and 9(22.5%)were isolated.It was accompanied by choroidal neovascularization,macular anterior membrane with retinal splitting,macular anterior membrane,pigment meningitis,macular hole,central serous choroidal retinopathy,and age-related macular degeneration;2.Frequency domain-OCT observed that the FCE sag layers were all RPE layers,and the OPR layer was mostly disappeared;3.The comparison between the simple FCE group and the FCE complication group indicated that there were differences in the component types of FCE complications in the simple FCE group and the FCE complication group(P < 0.05),among which,there were 2(8.3%)and 7(43.8%)separate types in the simple FCE group and FCE complication group,respectively.There was no significant difference between the two groups in gender,age,eye area,lesion width,lesion depth and lesion location(P >0.05);4.FCE group was compared with other groups and CNV group,and the lesion width,location distribution and classification were compared among the three groups,with statistically significant differences(P < 0.05).The average width of lesions in FCE group,CNV group and other complication group was(1026.88±367.81)um,(2428.8±1481.9)um,(817.14±437.42)um,and the depression locations were(759.96±427.2)um,(394.3±273.7)um,(1244.85±1355.32)um,respectively.There was no statistically significant difference between the three groups in gender,age,eye area and lesion depth(P > 0.05).Conclusion:1.Localized choroidal indentations tend to occur in middle age,with more cases in one eye and more cases in close eye,often associated with a variety of other diseases.2.RPE layer is the primary site of localized choroidal depression,which is closely related to damage to the outer layer of the retina,and the reason may be related to inflammatory infection or abnormal circulation in the outer layer of the retina.3.The width,type and location of FCE lesions may be related risk factors for rpe-related complications.The greater the width of choroidal depression,the closer it is to macular fovea,and the greater the risk of choroidal neovascularization.Isolated localized choroidal depression is prone to complications and has a high risk of choroidal neovascularization. |
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