The Value Of Cranial MRI In The Diagnosis And Prognosis Evaluation Of Brain Injury In Premature Infants

Objective: Based on the clinical data of 114 premature infants,the value of cranial MRI in the diagnosis and prognosis of brain injury in premature infants was analyzed to provide a basis for early intervention of brain injury in premature infants.Methods: A random sample of 114 premature infants who were hospitalized in our NICU from December 2016 to August 2019,were undergoing cranial MRI during hospitalization,and 3-6 months after discharge,the neurodevelopmental assessment was conducted in our department's child care clinic.According to the cranial MRI results,there were 63 cases in the brain injury group and 51 cases in the non-brain injury group.The clinical data of the subjects were retrospectively analyzed,and statistical processing was performed by SPSS22.0 statistical software and excell software.Result:1.Cranial MRI shows the type of brain injury in premature infantsAmong 114 cases of premature infants,63 cases of cranial MRI showed brain damage,the incidence was 55.26%,of which 7 cases were hemorrhagic brain damage with an incidence of 11.11%,51 cases with ischemic brain damage with an incidence of 80.95%,and combined 5 cases of two types of brain injury,the incidence was 7.93%.2.Gender,delivery methodAmong 114 cases of premature infants,66 cases were males and 48 cases were females.36 cases of brain damage occurred in male infants with an incidence of 54.54%;27 cases of brain injury occurred in female infants with an incidence of 56.25%.The difference was not statistically significant(P> 0.05).Among 114 cases of premature infants,32 cases were born naturally and 82 cases were cesarean section.16 cases of brain injury occurred during spontaneous delivery,the incidence was 50.00%;47 cases of brain injury occurred during cesarean delivery,the incidence was 57.31%.The difference was not statistically significant(P> 0.05).3.Gestational age,birth weightThere were 36 cases with GA <32 weeks and 19 cases of brain injury;36 cases with 32?GA <34 weeks and 28 cases with brain injury;42 cases with GA?34 weeks and 16 cases with brain injury.The difference was statistically significant(P <0.05).19 cases with BW <1500g,13 cases with brain injury;48 cases with 1500g?BW <2000g,30 cases with brain injury;29 cases with 2000g?BW <2500g,15 cases with brain injury;18 cases with BW?2500g,5 cases with brain injury.The difference was statistically significant(P <0.05).4.GESELL score,number of functional areas with neurodevelopmental delayThere were 42 cases(42/63)with a score of 85 or less in the brain injury group and 24 cases(24/51)with a score of 85 or less in the non-brain injury group.The difference was statistically significant(P <0.05).GESELL test: 0 function area lag behind,21 cases in brain injury group,27 cases in non-brain injury group;1 function area lag behind,12 cases in brain injury group,12 cases in non-brain injury group;2 function areas lag behind,15 cases in the brain injury group,8 cases in the non-brain injury group;there were ?3 function areas lag behind,15 cases in the brain injury group,and 4 cases in the non-brain injury group.The difference was statistically significant(P <0.05).Conclusion:1.In the premature infants with brain injury,the incidence of ischemic brain injury is higher than that of hemorrhagic brain injury.2.The incidence of brain injury in premature infants is not statistically different from that of premature infants in terms of gender and delivery methods.3.The smaller the gestational age and lower birth weight of premature infants,the more likely they are to have brain injury.4.The GESELL neural development test of premature infants counted in this study indicates that the brain injury group has worse neurodevelopment and more function areas after retention than the non-brain injury group.It is suggested that the abnormality of cranial MRI may indicate the late neurodevelopment of premature infants to a certain extent,and remind us to pay more attention to the close follow-up of preterm infants with abnormal cranial MRI,which is helpful for the early diagnosis and early intervention of the infants with abnormal neurodevelopment,so as to reduce the disability rate and improve the quality of life.