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Preoperation Evaluation Difference Research Between CT Imaging And Laparoscopy On 75 Patients With Advanced Ovarian Cancer

Posted on:2021-05-11Degree:MasterType:Thesis
Country:ChinaCandidate:Y J LiFull Text:PDF
GTID:2404330614464029Subject:Obstetrics and gynecology
Abstract/Summary:PDF Full Text Request
Objective: Analyzing the open surgery preoperation evaluation difference between CT imaging and laparoscopy on advanced ovarian cancer by comparing the examine results of these two technologies with the open-surgery results,respectively.Methods: Information of 75 patients in the Fourth Hospital of Hebei Medical University suspected to have advanced ovarian cancer,ranging from 09-2017 to 09-2019,was collected for this work.All patients went through regular preoperation examination,including learning about their disease history,the serum CA125 levels assessment,thorough gynecological examination,ultrasound examination,chest X-ray and enhanced whole abdomen CT examination.All patients were examined by laparoscopy,among whom 56 cases went through open surgery and the rest did not.All patients were examined by laparoscopy.SPSS version 23.0 was employed to analyze these results.Statistical significance was tested by chi-square test with standard of P <0.05.Based on that,the differences between CT imaging and laparoscopy were analyzed on their sensitivity,specificity,negative predictive value(NPV),positive predictive value(PPV)and accuracy to the 56 patients went through operations.Besides,the consistency of CT imaging and laparoscopy was also analyzed on the observed anatomical sites of both open-surgery patients and non-surgery patients.Results: 56 patients conducted open surgery,and their operation results were separately compared with CT imaging and laparoscopic evaluation results.According to the comparison,sensitivity,specificity,NPV and PPV of CT imaging and laparoscopy are 66% and 83%,89% and 93%,68% and 81%,and 88% and 93%,separately.The sum accuracies for them are 76% and 87%,respectively.According to chi-square test,sensitivity,specificity and NPV comparisons between CT imaging and laparoscopy showed P=0.000,meaning there are significantly statistic difference between them.Comparisons of PPV and accuracy between them showed P=0.244 and P=0.471,indicating there are no statistic difference between them therefore no significant difference for them.In the comparison of consistency between CT imaging and laparoscopy,P=0.274 revealing that they have high consistency on the identification of 6 anatomical sites from both operated patients and non-operated patients.Conclusions: Laparoscopy and CT imaging could optimize the evaluation on advanced ovarian cancer.Although CT imaging is a little less accurate than laparoscopy,they showed no significant difference on consistency of evaluating anatomical sites from operative patients and non-operative patients.In consideration of laparoscopy is more accurate in identifying nidus less than 1cm in diameter,it is more viable to evaluate the operation feasibility and make individualized treatment plans.However,this study has small amount of samples.Therefore,the results needs to be further tested in bigger sample array if more definite conclusions want to be acquired.
Keywords/Search Tags:Advanced ovarian cancer, CT imaging, Laparoscopy
PDF Full Text Request
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