The Value Of Laparoscopy Exploration For Advanced Ovarian Cancer

Backgroud & Objective:Ovarian cancer is the leading cause of death among gynecologic malignancies. The prognosis of early-stage disease is significantly better than late-stage disease, with 5-year survival varying from 80%-93% (stage 1/2) to <30% (stage 3/4).The unfavorable prognosis of this disease is largely due to the lack of specific symptoms and early detection methods. Approximately 75% of the cases are stage Ⅲ or Ⅳ when first diagnosed.The FIGO cancer report 2012,the prognosis of epithelial ovarian,fallopian,and peritoneal maliganance is stage of the cancer at diagnosis,histological type and grade,maximum diameter of residual disease after cytoreductive surgery. To achieve the optimal primary cytoreduction is an important method of treatment of ovarian malignant tumors. In this paper, through collecting in shandong university qilu hospital for treatment of 20 cases of laparoscopic exploration evaluation after joint laparotomy or laparoscopy surgery patients with advanced ovarian malignant tumors, study the effects of laparoscopic exploration of comprehensive assessment ovarian malignant tumor patients achieve ideal tumor cells remove factors and prognosis.Method:In this study,Collecting through November 2011 to April 2015 in shandong university qilu hospital 20 of malignant ovary(including fallopian tubes) tumor patients whose operation completed jointly by two chief physicians. Firstly,laparoscopy evaluation is made,than joint laparotomy or laparoscopy surgery, after the postoperation fist-line chemotherapy regimens is used, finally regular follow-up.Analyze the effect of laparoscopic exploration evaluation malignant ovary (tube) tumor patients achieve ideal tumor cells remove factors.Results:Analyzing the he group A (optimal primary cytoreduction) and group B (suboptimal primary cytoreduction) of two groups of clinical situation,operation situation, situation of pathology.The age use the t test, the exact use the probability test.As result disply age CR, according to the results of two groups (p= 0.866) and ovarian histological type (p= 0.06) has no statistical significance,.However,serum CA125 (p = 0.003), liver area (p = 0.0007) and spleen (p = 0.001) metastases, greater omentum contracture in cake (p = 0.002), ascetic fluid (p = 0.005) and the rectouterine excavation planting focal(p = 0.0008) andFIGO stage (p = 0.003) has statistical significance.Conclusion:Laparoscopy for advanced ovarian cancer diagnosis, assessment of advanced ovarian cancer primary cytoreduction surgery can achieve optimal primary cytoreduction and secondary cytoreduction can provide effective reference value;Serum CA125, liver metastatic lesions, spleen metastatic lesions, ascetic fluid, rectouterine excavation planting focal and FIGO stage are the factors influencing the ideal cells to destroy the loss.