| Objective: The purpose of this study was to investigate the effect of the interval between percutaneous transhepatic gallbladder drainage and(PTGBD)and laparoscopic cholecystectomy(LC)on the technical difficulty and postoperative complications of cholecystectomy,and to determine the optimal timing for laparoscopic cholecystectomy after PTGBD.Methods: The clinical data of 77 patients with moderate and severe acute cholecystitis who received LC after PTGBD in Shengjing hospital of China Medical University from January 2015 to September 2019 were retrospectively analyzed.According to the time of selective LC,the patients were divided into three groups: LC within 2 weeks after PTGBD(n=16),LC within 2 weeks to 2 months(n=29),and LC within 2 months to 4 months(n=32),to observe the therapeutic effect of PTGBD and selective LC.Results: All 77 patients had successfully completed PTGBD,and no serious complications such as bile leakage,biliary bleeding,pneumothorax,colon perforation caused by puncture were found in all patients.One patient underwent PTGBD again due to detubation,and one patient had sustained high postoperative fever.There were no significant differences in preoperative review of gallbladder wall thickness(4.11±1.31)mm vs(4.09±1.82)mm vs(3.98±1.41)mm,opreation time(80.25±27.52)min vs(85.59±35.70)min vs(79.72±30.05)min,intraoperative blood loss(35.63±29.20)ml vs(28.97±36.26)ml vs(22.50±15.96)ml,postoperative hospital stay((5.81±1.76)day vs(4.90±1.76)day vs(5.03±2.02)day),total hospitalization expenses(42532.09±8988.88)yuan vs(41404±9899.42)yuan vs(43921.98±9558.80)yuan and pathological grade in the 3 groups(P values were 0.951,0.749,0297,0.271,0.587,0.098).Conclusion:Laparoscopic cholecystectomy is safe and effective within 2 weeks after percutaneous transhepatic gallbladder drainage,and can shorten the time of tube insertion,thus improving the quality of life of patients. |
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