| Objective:Set up a ‘Cognitive Detection System Platform' to screen the enrolled patients,and observant clinical curative effect among ‘Tiaoshen Yizhi' acupuncture combined with Kaixin San,which originated from the?Beiji Qianjin Yao Fang?written by Sun Simiao in the Tang Dynasty,‘Tiaoshen Yizhi' acupuncture and Kaixin San in treatment of patients with Non-dementia after cognitive ischemic stroke.Hoping to provide timesaving,human,material,and feasible cognitive detection platform for clinical,as well as a safe,less side effects and effective TCM basic treatment plan for patients with predementia.Methods:This study is attached to the pilot project of clinical collaboration of traditional Chinese and western medicine for major and difficult diseases(cerebral infarction).64 patients who met the criteria from March 2018 to September 2019 in Shaanxi Province Chinese Medicine Hospital and Xi'an Chinese Medicine Brain Disease Hospital were randomly divided into three groups.As of the time of data statistics,one case in control group I fell off due to poor compliance,one case in control group II was eliminated due to misunderstanding,and one case fell off due to poor compliance.The control group ?(n=20)was given Tiaoshen Yizhi acupuncture treatment on basic treatment,the control group ?(n=19)was given oral Kaixinsan treatment on basic treatment,and the treatment group(n=22)was given basic treatment Tiaoshen Yizhi needle and Kaixinsan were given to the three groups for 3 months.According to the clinical and experimental characteristics of PSCIND,the best evaluation scale is selected to form a "cognitive detection system platform",and the evaluation platform is used to compare the three groups of simple mental state scale(MMSE)scores before and after treatment,and the Huashan version of auditory words Learning Test(AVLT-H)score,Shape Connection Test A and B scale score(STT AB),Animal Word Fluency Scale score(AFT),Boston Naming Test(BNT),Social Activity Function Scale(FAQ)score.Results:Observation before treatment: There were no significant differences in the indicators of the three groups of patients(p> 0.05);observation after treatment: 1.The memory function(AVLT-H total score)of the patients in the treatment group was significantly improved compared with the two control groups(p <0.01),especially Immediate recall and recognition;2.The executive function of the treatment group(STT-A,STT-B score)isbetter than the control group ?,control group ?(p <0.05),and the language(AFT,BNT score)three The difference between the two groups was not significant(p> 0.05);3.The overall cognitive status and social activity function(MMSE,FAQ score)of the patients in the treatment group were better than those in the control group ? and control group ?(p<0.05),of which the treatment group MMSE The score was significantly better than the control group ?(p <0.01).Conclusion:Through observation,it has been found that Tiaoshen Yizhi acupuncture combined with Kaixinsan has the effect of improving cognitive function,and acupuncture combined with medicine is superior to each single therapeutic effect,especially in improving memory,executive function and daily living ability.The cognitive detection system platform can facilitate the early identification of people with cognitive impairment.The treatment methods and identification methods are easy to operate,have high safety and low cost,and can be widely used in clinical applications. |
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