The Correlation Of Axillary Osmidrosis With Lipid Profiles And Body Mass Index

Objective:The objective of our study is to investigate whether serum lipid profile and body mass index are potential risk factors for axillary osmidrosis(AO).It may provide a new idea for the adjuvant treatment and pathogenesis of axillary osmidrosis.Methods: According to our criteria,from January 1,2016 to December 31,2018,203 patients with axillary osmidrosis were treated in the Department of plastic surgery,affiliated Hospital of Qingdao University as the experimental group and 94 patients without axillary osmidrosis as the control group,a total of 297 cases were included in this study.Age,sex,height,weight,total cholesterol(TC),high density lipoprotein(HDL),low density lipoprotein(LDL),triglyceride(TG)and other clinical data were obtained from clinical data for stratified analysis,univariate and multivariate Logistic regression analysis.The purpose was to investigate the effects of lipid profiles and BMI on the incidence of AO.Results: The study included patients with AO(66 men/137 women;average age 22.7 years)and the control group(16 men/78 women;average age 23.3 years).Compared with the control group,the body weight,BMI,TC,TG and LDL levels of the patients with axillary osmidrosis were significantly higher than those of the control group(P < 0.001,P < 0.001,P =0.011),but there was no significant difference in HDL between the two groups.Logistic regression analysis showed that BMI was a risk factor for axillary osmidrosis(OR:1.3,95%CI:1.2-1.4,P < 0.0001).The correlation between BMI and AO remained stable after adjusting confounding factors(OR:1.6,95%CI:1.2-2.0,P=0.0013).It is suggested that the high level of BMI has a higher risk than the low level of BMI,which is 6.1 times higher than that of the low level of AO(95% CI: 2.7-13.4,P < 0.0001).The positively correlation between BMI and AO remained stable after multiple logistic regression analysis(OR:28.9,95%CI: 4.6-181.9,P=0.0013).TC,TG and LDL in serum lipid profile are risk factors of axillary osmidrosis(TC,OR:1.9,95%CI:1.5-2.5,P<0.0001;TG,OR:3.6,95%CI:2.0-6.2,P<0.0001;LDL,OR:2.6,95%CI:1.4-4.7,P=0.0028).After adjusting the confounding factors,the correlation between TC,TG,LDL and AO still exists stably(TC,OR:2.0,95%CI:1.4-2.8,P < 0.0001;TG,OR:3.6,95%CI:2.0-6.5,P < 0.0001;LDL,OR:3.6,95%CI:1.7-7.7,P=0.0008).After grouping the serum lipid profile TG,LDL,the risk of AO in the high level group was higher than that in the low level group.The relationship was 2.3 times and 2.8 times in high level of TG and LDL higher than that of the low level after multiple logistic regression analysis(95% CI: 1.1-4.5,P=0.0182;95% CI: 1.3-5.9,P=0.0071).Conclusion: The results of this study show that BMI,TC,TG,and LDL are risk factors for AO and positively correlated with the risk of axillary osmidrosis.Therefore,BMI,TC,TG,and LDL may be used as potential risk factors for AO in clinical evaluation,providing a reference for subsequent clinical adjuvant treatment.