Diagnostic Value Of CT-guided Percutaneous Lung Biopsy For Small Pulmonary Nodules

Objective To evaluate the clinical diagnostic value of CT-guided percutaneous needle biopsy(PNB)for pulmonary solid nodules,pure ground-class nodules and mixed ground-glass nodules with diameter≤20mm.Methods The data of 109 patients undergoing CT-guided percutaneous needle biopsy of pulmonary nodules(≤20mm)between January of 2017 and June of 2019 in our hospital were collected and the sampling of different subtypes of nodules,pathological results and intraoperative and postoperative complications were analyzed retrospectively.Results A total of 109 cases of pulmonary nodules were punctured and technical success of CT-guided PNB for small(≤20mm)lung nodules was 100%.89 patients were definitely pathological diagnosed,with a diagnosis rate of 81.7% 89/109).There were 46 cases of malignant lesions,accounting for 42.2% of the total pulmonary nodule patients,of which the malignant rate of solid pulmonary nodules was 41.6%.The malignant rate of subsolid nodules was 42.4%,of which,the malignant rate of pure ground glass nodules of the lung was 43.4%,and the malignant rate of mixed ground glass nodules of the lung was 40.7%.The diagnostic rates of pulmonary solid nodules,pure ground-class nodules and mixed ground-glass nodules were 91.7%,69.6% and88.9%respectively,there were significant differences among them(P>0.05).The diagnosis rates of lesions among5 mm ~10mm and 10mm~20mm in diameter were70.6%and83.7%,there were no statistical significance between them(P<0.05).The total complications of pneumothorax and pulmonary hemorrhage was 9.1% and32.1%respectively.The complications of pneumothorax insolid nodules,pure ground-class nodules and mixed ground-glass nodulewas 11.1%,8.7% and 7.4%,with no statistical differences among them(P<0.05).The complication of pulmonary hemorrhage in pulmonary solid nodules,pure ground-class nodules and mixed ground-glass nodules were 11.1%,45.7% and37%respectively,there were significant differences among them(P<0.05).Conclusion CT-guided percutaneous needle biopsy(PNB)has high diagnostic value for pulmonary solid nodules,pure ground-class nodules and mixed ground-glass nodules with diameter≤20mm.However,the diagnosis rate of pure ground-class nodules is lower,and the complication of hemorrhage of pure ground-class nodules and mixed ground-glass nodules is higher.Therefore,we should pay more attention to the puncture biopsy of pulmonary nodules with different densities in clinical work.