Exploring Changes In Breast Cancer Therapy Based On Clinical Practice Guidelines

Objective:To explore the changes in breast cancer clinical practice guidelines and the similarities and differences between domestic and foreign guidelinesMethods:Based on the clinical practice guidelines for breast cancer,this paper discusses chemotherapy,targeted therapy,endocrine therapy,and radiotherapy for breast cancer using the literature review method,the guideline research method,and the inductive analysis method.Gap analysis.Results:Throughout the changes of breast cancer diagnosis and treatment guidelines,with the introduction of the concept of precision medicine,the treatment of breast cancer has gradually become more precise and meticulous.With the advancement of medicine,the development and marketing of new drugs have greatly changed and improved the treatment decision of breast cancer.In terms of neoadjuvant therapy,adjuvant therapy,and advanced rescue therapy for breast cancer,the guidelines have similarities and differences in indications and treatment options,but the similarities are greater than the differences.Differences,medical insurance policies,etc.Conclusions:1 ChemotherapyChemotherapy is the main method of systemic treatment,based on anthracyclines and yews.Indications are based on tumor size(T)?risk classification?molecular classification?multi-gene detection technology to assist decision-making and continue to be precise.2 Targeted therapyThe HER family is currently the main research target for breast cancer.With the deepening of original drug research,the discovery of new targets,new targeted drugs have been launched,and the concept of targeted therapy is also constantly doing"addition and subtraction." The treatment duration of single-agent trastuzumab has been continuously explored and compared in clinical trials for 1 year,6 months,9 months,and 2 years,and finally the standard treatment time of 1 year has been determined.Upgrade from single target to dual target and multi target therapy.3 Endocrine therapyEndocrine therapy is coming from the initial TAM?AI era?post-AI era.One is the extension of treatment,and the other is the continuous development and marketing of endocrine drugs.In terms of treatment duration,from the first 2 to 3 years?5 years?10 years of treatment.