Effect Of The Program Of Enhanced Recovery Of Surgery (EUAS) On Prognosis And Postoperative Inflammatory Response In Patients Undergoing Thoracoscopic Lobectomy

Objectives:This study intends to compare the effects of rapid rehabilitation schemes and traditional schemes on the prognosis and inflammatory response of patients undergoing thoracoscopy lobectomy,providing a theoretical basis for better application of rapid rehabilitation schemes to this type of surgery.Medthos:Forty patients with ASA grades ?-?,who were diagnosed with lung cancer before surgery and needed to undergo thoracoscopic lobectomy were randomly divided into two groups:the control group(n=20)and the study group(n=20).The perioperative management was performed according to the traditional scheme,and the patients in the study group were perioperative management according to the rapid recovery clinical scheme.The concentrations of inflammatory factors(IL-1?,IL-6,IL-8,IL-1?,IL-6,IL-8,IL-10,TNF-?),perioperative dose of opioids,placement time of thoracic drainage tube and postoperative hospital stay,postoperative VAS score(Visual Analogue Score),postoperative complications and other related clinical prognostic indicatorsResults:Compared with the T1 time point,the serum inflammatory factors(IL-1?,IL-6,IL-8,IL-10,TNF-?)concentrations in the two groups of patients were significantly increased at the T2,T3 and T4 time point(p<0.05).Compared with the T1 time point of the control group,the serum inflammatory factor(IL-1?,IL-6,IL-8,IL-10,TNF-?)concentrations of the study group patients at the T1 time point were not significantly different(p>0.05);Compared with the control group at time points T2,T3,and T4,the serum inflammatory factors(IL-1?,IL-6,IL-8,IL-10,TNF-?)concentrations in the study group were significantly reduced at each time point(p<0.05).);Compared with the control group,the perioperative opioid dose of patients in the study group was significantly reduced(p<0.05),the indwelling time of the thoracic drainage tube was significantly shortened(p<0.05),and the postoperative VAS score was significantly reduced(p<0.05).),The length of postoperative hospital stay was significantly shortened(p<0.05),and the incidence of pulmonary complications during hospitalization was significantly reduced(p<0.05).Conclusions:The ERAS program used in thoracoscopy lobectomy can effectively reduce the release of inflammatory factors,reduce pain,shorten the length of hospital stay,and reduce pulmonary complications.