Analysis Of Correlation Between Local Muscle Content (Hip And Waist) And Bone Mineral Density At Different Ages

Objective:Research on the correlation between muscle content and bone mineral density is a hot spot in the field of osteoporosis.There are many new viewpoints on the influence of muscle content on bone mass.This study mainly analyzed the relationship between "lumbar muscle content and lumbar bone mineral density" and "hip muscle content and hip bone mineral density" at different ages.It also analyzed the clinical data of"muscle-bone" in detail.It is hoped that:(1)there will be further analysis data on the age and location of "muscle content-bone change";(2)functional training for different age groups in clinic,and There are further guidance suggestions to prevent bone loss.Methods:(1)A cross-sectional study was conducted on 8305 subjects over 50 years old who had undergone routine health examinations at Affiliated Second Hospital,Soochow University from June 2008 to December 2013.(2)BMD(lumbar spine and hip)and local muscle content(hip and waist)were measured using dual-energy X-ray absorptiometry methodology(DXA),and all the data were sorted out.(3)The data were divided into two groups according to gender,each group was divided into four groups(50-59,60-69,70-79,?80 years old)according to age respectively.The trend of local muscle content and bone mineral density with age was shown by polygraph.The relationship between local muscle content and bone mineral density was analyzed by partial correlation analysis and multiple linear regression.Results:(1)There was a positive relationship between hip muscle content and femoral neck BMD in both males and females at 50-59,60-69 years old(P<0.05),but there was no correlation at 70-79,?80 years old.(2)There was no correlation between waist muscle content and lumbar spine BMD in both males and females,except for the negative relationship in males at 70-79 years old(P<0.05).Conclusions:Hip muscle content has a significant effect on femoral neck bone mineral density between 50 and 70 years old in this study group.After 70 years old,hip muscle content has no significant effect on femoral neck bone mineral density.There is no correlation between lumbar muscle content and lumbar bone mineral density.There is a negative correlation between lumbar muscle content and lumbar bone mineral density in 70-79 years old group.Therefore,based on the research viewpoint of oligomyosis and osteoporosis,this study suggests that people aged 50-70 should pay attention to the increase of hip muscle(lower limb muscle)content in order to improve bone mass;people over 70 years old should pay more attention to the prevention of osteoporosis risk factors(such as falls,bone metabolism indicators,etc.)besides muscle content.