Effect Of Preoperative Dexamethasone On Gastrointestinal Motility After Gastrointestinal Surgery

Background and Aim:Most patients undergoing abdominal surgery,especially those involving the stomach and intestines,usually experience a transient episode of impaired gastrointestinal motility.The main purpose of our study was to determine whether intravenous injection of low-dose dexamethasone before surgery can promote the recovery of gastrointestinal function in patients undergoing gastrointestinal surgery.Methods:In this single-center,double-blind randomized controlled trial,we studied a total of 126 cases of malignant or benign pathology due to electronic gastrointestinal examination but required surgery and the patient himself voluntarily chose to undergo open gastrointestinal surgery or abdominal Patients with endoscope-assisted gastrointestinal surgery(age 18-80 years).Under induction of anesthesia,patients in the treatment group(n=64)were given intravenous injection of 8 mg dexamethasone,while patients in the control group(n=62)were given intravenous saline.Observe the relevant indexes of postoperative recovery of the two groups of patients.Results:We found that the average time for recovery of intestinal ventilation during the postoperative recovery of patients in the treatment group.that is,patients who received a small dose(8 mg)of dexamethasone by intravenous injection during anesthesia induction,was significantly reduced.8 hours(p<0.05).And we also found that the patients in the dexamethasone group had significantly better abdominal distension on the third-day after surgery than in the saline group(p<0.05),and the patients in the dexamethasone group had a shorter tolerance time to the liquid diet(p<0.01).However,there were no significant differences in other secondary outcomes between the two groups.The other secondary outcomes we observed included postoperative pain score,incidence of complications,length of hospital stay,and time of first bowel movement.Conclusions:A single intravenous injection of a small dose(8 mg)of dexamethasone during induction of anesthesia can significantly reduce the recovery time of intestinal ventilation after gastrointestinal surgery,improve the patient's abdominal distension at 72 hours,and improve the patient's liquid diet Tolerance.Although further research is needed to confirm our results,we recommend that a single small dose(8 mg)of dexamethasone be injected intravenously during the induction of anesthesia to improve the patient if gastrointestinal surgery patients'physical conditions permit Postoperative recovery.