Risk Factors And Profile By Phenotypic ASCO Of Ischemic Stroke In The Young

Objectives: 1.To investigate the distribution of ASCO etiology in young patients with ischemic stroke in the region.2.To explore the relationship between traditional cerebrovascular risk factors and ASCO subtypes in young patients with ischemic stroke in the region.Methods: A total of 114 consecutive 18-45 year-old patients with ischemic stroke admitted in the Department of Neurology of Yueyang second people's Hospital from January 2016 to October 2019 were collected.ASCO classification was used to investigate the etiological distribution of young patients with ischemic stroke and the correlation between hypertension,diabetes,hyperlipidemia,smoking and other traditional cerebrovascular risk factors and ASCO subtypes.Results: Small-vessel stroke is most common among ASCO class 1subtypes,followed by atherosclerotic stroke.There is no statistical differences in the incidence of gender,smoking history,and hyperlipidemia among patients in each subtype(p>0.05).There was significant difference in the incidence of hypertension among patients in each subtype(p<0.05).Regression analysis of traditional cerebrovascular risk factors such as hypertension,diabetes,hyperlipidemia,smoking and ASCO subtype 1 showed that diabetes was associated with atherosclerotic stroke(OR = 7.289,p= 0.004),hypertension is related to the occurrence of atherosclerotic stroke(OR = 5.753,p = 0.042),and also to the occurrence of small-vessel stroke(OR = 6.052,p = 0.011).Conclusion: Diabetes,hypertension and atherosclerosis are the most common risk factors of ischemic stroke in young adults in Yueyang region,and small-vessel stroke may be the most common cause of ischemic stroke in young adults in the region.