| Objective: In this study,patients with slow transit constipation were taken as the objects to study the clinical efficacy of rhubarb mirabilite umbilicus dressing combined with biofeedback in the treatment of slow transit constipation,which was compared with oral Prucalopride Succinate Tablets,to compare the differences of various indicators before and after treatment of the two methods,and to evaluate the clinical efficacy and cure rate of the two groups,providing new ideas for the treatment of clinical slow transit constipation.Method: 60 patients aged between 18 and 75 years who were treated in department of anorectal outpatient department or inpatient department of the First Affiliated Hospital of Anhui University of Traditional Chinese Medicine from November 2018 to November 2019 and definitively diagnosed as slow transit constipation were selected.According to the random number table method,60 cases of research subjects meeting the standard were randomly divided into a treatment group and a control group of 30 cases each.For patients in control group,Prucalopride Succinate Tablets was given orally,2mg,once a day;while for patients in treatment group,rhubarb mirabilite 4-5g on Shenque acupoint was added on the basis of biofeedback for continuous 30 days.In addition,both groups were instructed to defecate regularly and have reasonable diets.Constipation symptom score,life quality score,Glazer assessment of pelvic floor and anorectum manometry before and after treatment of patients were observed,and the clinical efficacy was determined.Result: 1.Before treatment,statistical analysis was performed on relevant data of age,sex,and disease duration of the two groups of patients.The calculated values were P>0.05,and the differences between the two groups were not significant.Therefore,the clinical data of the two groups are comparable.2.Before treatment,there was no statistically significant difference in constipation symptom score between the comprehensive treatment group and the control group(P >0.05),which was comparable.After treatment,the scores and total scores of the twogroups were reduced compared with those before treatment;besides abdominal distension integral,rhubarb mirabilite apply umbilical joint biofeedback groups dung shape,defecation time interval integral,defecation difficult points and enthusiastic vexed points were significantly lower than that in control group,after statistics analysis,the differences were statistically significant(P<0.05),two groups of treatment are to improve constipation symptoms,and comprehensive quality,and the treatment group in improving the dung,defecate difficulty and defecation time interval is better than that in control group.After treatment,the scores of PAC-QOL were significantly improved in the two groups which compared with the results those before treatment(P<0.01).The PAC-QOL score of the treatment group was significantly better than that of the control group(P<0.01).3.The pelvic floor electromyography and anorectal pressure in the treatment group were significantly improved after treatment than before treatment(P <0.05);in control group,the pelvic floor electromyography before and after baseline and rapid contraction phase,as well as anal canal resting pressure and systolic pressure in anorectal pressure measurement after treatment,were improved in comparison with those before treatment(P<0.05);after treatment,the pelvic floor electromyography evaluation and anorectal pressure improvement in treatment group was more significant than that in biofeedback group(P<0.01).4.In the treatment group,the cure rate was 30.00% and the effective rate was93.33%.The cure rate of the control group was 20.00% and the effective rate was73.33%.After statistical analysis,the difference was statistically significant(P<0.05),and obviously the treatment group was better than control group.Conclusion: Rhubarb mirabilite umbilicus dressing combined with biofeedback was effective in the treatment of patients with slow transit constipation,and had certain effects on improving patients' clinical symptoms,life quality and defecation difficulty.Its efficacy was better than Prucalopride Succinate Tablets that was taken orally to promote gastrointestinal motility,so it was worth popularizing in clinic. |
PDF Full Text Request