Microsurgical Treatment And Prognosis Of Pilocytic Astrocytoma

Objective:To investigate the extent of tumor resection and postoperative survival of pilocytic astrocytoma patients,and to evaluate the efficacy of micro-surgical treatment of pilocytic astrocytoma.Methods:The clinical data of 67 patients with pilocytic astrocytoma,who underwent tumor resection in the first affiliated hospital of Xinjiang Medical University from September 2010 to September 2019,were analyzed retrospectively.Results: A total of 67 patients underwent tumor resection in this study(33males and 34 females =1:1.03,aged 22 months to 71 years),including 36 cases(53.7%)of gross total resection,6 cases(9.0%)with near total resection,11 cases(16.4%)of subtotal resection,11 cases(16.4%)of partial resection and only biopsy in 3 cases(4.5%).The postoperative complications mainly included hydrocephalus in 5 cases,intracranial infection in 6 cases,and pulmonary infection in 5 cases.Follow-up was available in patients via outpatient or telephone,the follow-up periods were 2 to 99 months,during which tumor recurrence or progression were found in 11 patients,three of whom performed re-resection of tumors.No tumor recurrence was found following gross total tumor resection during the follow-up observation.Conclusion: Pilocytic astrocytomas are relatively rare and primarily treated by surgery,the patients who underwent micro-surgeries of gross total tumor resection had the best prognosis,and incomplete tumor resection was an independent risk factor affecting the prognosis of patients in this study.