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Retrospective Analysis Of Risk Factors For Recurrence And Progression Of Non-muscle Invasive Bladder Cancer After TURBT Incontinence

Posted on:2020-01-11Degree:MasterType:Thesis
Country:ChinaCandidate:Z M T A K B AiFull Text:PDF
GTID:2404330602963330Subject:Surgery
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Objective: To study the influencing factors of recurrence and progression after TURBT in non-muscle invasive bladder cancer.Methods: Retrospective analysis of the cases of patients with bladder tumor diagnosed in our department of urology from January 2007 to December 2016.After TURBT,the patients with NMIBC were diagnosed by the senior doctor of pathology in our hospital.Survival analysis of age,size of tumor,size of tumor,number of tumors,grade of tumor,stage of tumor,immediate intravesical instillation,maintenance of perfusion,and postoperative maintenance of different bladder infusion drugs,and definition of bladder tumor recurrence or Further progression of the tumor was the endpoint event.Log-Rank test and kaplan-Meier method were used to analyze the difference in disease-free survival of bladder tumor recurrence and progression.The Cox proportional hazard regression model was used for multivariate analysis of NMIBC patients.Independent risk factors for post-recurrence and progression.RESULTS: A total of 511 patients with a pathologic diagnosis of NMIBC were included in the study.The mean age of the patients was 60.8 years,male: female = 3.7:1,follow-up was 6 to 124 months,and 151 patients had recurrence.(Total recurrence rate was 29.5%),and 27 patients progressed(total progression rate 5.5%).Univariate analysis found that the size of the tumor,the number of tumors,the grade of the tumor,the stage of the tumor and the recurrence of NMIBC tumors were statistically significant(P<0.05).The tumor size,tumor grade,tumor stage,tumor number and tumor number were The progress of NMIBC was statistically significant(P<0.05).Cox regression model multivariate analysis found that the pathological grade of tumors in relapsed patients can significantly affect tumorrecurrence and progression.Conclusion: Tumor pathological grade is an independent risk factor for NMIBC recurrence and progression,and tumor grade affects the progression of NMIBC.Conclusion: Tumor pathological grade is an independent risk factor for NMIBC recurrence and progression,and tumor grade affects the progression of NMIBC.
Keywords/Search Tags:Non-muscle-invasive bladder cancer, Recurrence, Progress
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