Application Of Magnetic Resonance Diffusion Kurtosis Imaging In Marginal Infiltration Zone Of Cerebral Alveolar Echinococcosis

Objective: To investigate the parenchymal area,marginal zone(0~10mm),edema zone and normal control area of cerebral alveolar echinococcosis by quantitative analysis of magnetic resonance diffusion kurtosis imaging,and to defining the extent of the lesion and surrounding tissue.Methods: From December 2018 to January 2019,16 cases were clinically and pathologically diagnosed of cerebral alveolar echinococcosis with 30 target lesions,which were subjected to MRI scan,enhanced scan and magnetic resonance diffusion kurtosis imaging.quantitative index(anisotropy,mean diffusion coefficient,mean diffusion kurtosis)of magnetic resonance diffusion kurtosis imaging in lesion parenchyma,marginal zone,edema area and contralateral normal brain parenchyma area.Results:There was no significant difference in FA values between the parenchymal and marginal zones of the lesion,the parenchymal and edema zones,and the marginal zone and edema of the lesions(P>0.05).The differences between the other groups were statistically significant(P>0.05);In the comparison of MD values,there was no statistically significant difference between the lesion's parenchymal zone and the marginal zone(P>0.05),and the differences between the other groups were statistically significant(P<0.05).In the comparison of MK values,the lesion's parenchymal zone and the marginal zone were different There was no statistical significance(P>0.05),the differences between the other groups were statistically significant(P<0.05).Conclusion:The quantitative analysis of magnetic resonance diffusion kurtosis imaging revealed that echinococcus infiltration may exist within a range of 0 to 10 mm around the lesion of the cerebral alveolar echinococcosis,which can provide imaging basis for clarifying the lesion and the surrounding brain tissue.