Systematically Evaluate The Effect Of Chinese Medicine On The Intestinal Flora Of Patients With Type 2 Diabetes

Objective:To systematically evaluate the effect of Chinese medicine on the intestinal flora of patients with type 2 diabetes,and to provide new diagnostic ideas and evidence-based evidence for the clinical treatment of type 2 diabetesMaterials and Methods:CNKI,Wanfang Data Academic Papers Database,Weipu Chinese Scientific Journal Full-text Database,Pubmed were retrieved,and clinical studies of T2DM patients treated with Chinese medicine published before December 2019 were retrieved Literature screening was performed in strict accordance with the inclusion and exclusion criteria,and the included data were entered into Rev Man 5.3 software for meta-analysis.According to the nature and unit of the included index,the weighted mean difference WMD or standardized mean difference SMD is selected as the combined statistics.Outcome indicators:number of intestinal anaerobic bacteria(Bifidobacterium,Bacteroides,Lactobacillus);number of intestinal aerobic bacteria(Enterobacter,Enterococcus,yeast);blood glucose levels(FPG,2hPG,HbAlc);blood lipid levels(TC,TG,HDL-c,LDL-c)Conclusions:1.Compared with pure western medicine treatment,the combination of traditional Chinese and western medicine has certain advantages in the growth of intestinal anaerobic bacteria(Bifidobacterium,Bacteroides,Lactobacillus)in patients with diabetes,and the difference is statistically significant.2.Compared with pure western medicine treatment,the combination of traditional Chinese and western medicine has certain advantages in inhibiting intestinal aerobic bacteria(entercobacteria,enterococci,yeast)in patients with diabetes,and the difference is statistically significant.3.Compared with pure western medicine treatment,the combination of traditional Chinese and western medicine has certain advantages in reducing the blood glucose(FPG,2HPG)of diabetic patients,and the difference is statistically significant.4.Compared with western medicine treatment alone,the combination of traditional Chinese medicine and western medicine has certain advantages in reducing blood lipids(TC,TG,HDL-c,LDL-c)in patients with diabetes,and the difference is statistically significant.