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Clinical Study Of Visual Quality After Personalized Implantation Of Aspheric Intraocular Lens

Posted on:2020-01-03Degree:MasterType:Thesis
Country:ChinaCandidate:D HuangFull Text:PDF
GTID:2404330602955335Subject:Clinical Medicine
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Objective:The OPD-Scan? optical visual quality analyzer(Nidek,Gamagori,Japan)is used to compare the visual quality of aspheric IOL with different SA by the personalized selection and aspheric IOL at random were implanted in order to provide reference for the personalized selection of IOL.Method:A total of 82 patients(86 eyes)with age-related cataract in the period of September 2016 to December 201 8 from our hospital including 46 females(49 eyes)and 36 males(37 eyes)with an age between 50 to 93years old(a mean age of 67.21±10.15 years old)were taken into the study excluding patients with other medical history of the eye,systemic disease affecting vision,and history of ocular surgery.In this study,all patients were randomly divided into two groups by a randomized controlled study.In group A(42 eyes,male 21 eyes,female 21 eyes),aspheric IOL with different SA were implanted on the basis of the corneal SA with a 6mm diameter pupil before surgery in order to reserve+0.1?m of the whole eye SA after surgery with the formula is that whole eye SA is equal to the algebra sum of IOL SA and corneal SA after surgery.In group B(44 eyes,male 16 eyes,female 28 eyes),aspheric IOL at random were implanted.IOL power was calculated by using the SRK/T formula.In order to meet the needs of patients with better distance vision and certain near vision after surgery,the target refraction was set to-0.5D.We collect and analyze the date of the patients'UCVA,BCVA.Under a pupillary diamater of 4mm,We collect and analyze the date of the higher order aberration(SA-RMS,tHOA-RMS,TC-RMS,TT-RMS)of the Cornea and whole eye and the higher order aberration(tHOA-RMS,TC-RMS,TT-RMS)of the intraocular and the MTF and SR of whole eye on the first day after surgery,one week after surgery and one month after surgery.Under a pupillary diamater of 6mm,We collect and analyze the date of the SA-RMS of the Cornea and whole eye and the MTF and SR of whole eye on the first day after surgery,one week after surgery and one month after surgery.All data is analyzed by the Application SPSS21.0 Software Package.The counting data were analyzed by chi-square test.The measurement data should must be analyzed by normality test.If the data do not accord with the normality distribution,the non-parametric rank sum test is used.If the data accord with the normality distribution,then analysis of variance is used.If the data is consistent with variance homogeneity,the t-test is used.If-not,the t'-test is used.A value of p<0.05 was taken as statistically significant.Result:1 Vision1.1 UCVAThe UCVA of patients in group A and B were improved after surgery.There was no significant difference in UCVA between the two groups before surgery(P>0.05).There was no significant difference in UCVA between the two groups(P>0.05)on the first day after surgery,first week after surgery and first month after surgery.On the first day after surgery,first week after surgery and first month after surgery,UCVA in group A was statistically significant compared with that before surgery,and that in group B was also significant(group A:P<0.05)(group B:P<0.05).1.2 BCVAThe BCVA of patients in group A and B were improved after surgery.There was no significant difference in BCVA between the two groups before surgery(P>0.05).There was no significant difference in BCVA between the two groups(P>0.05)on the first day after surgery,first week after surgery and first month after surgery.On the first day after surgery,first week after surgery and first month after surgery,BCVA in group A was statistically significant compared with that before surgery,and that in group B was also significant(group A:P<0.05)(group B:P<0.05).2 High-order aberration2.1 Corneal high-order aberration2.1.1 High-order aberrations of the cornea before and after surgery2.1.1.1 Under a pupillary diamater of 6mmGroup A:Corneal SA-RMS under a pupillary diamater of 6mm before surgery was compared with that one day after surgery,one week after surgery,and one month after surgery,there was no significant difference between the groups(P>0.05).Group B:Corneal SA-RMS under a pupillary diamater of 6mm before surgery was compared with that one day after surgery,one week after surgery,and one month after surgery,there was no significant difference between the groups(P>0.05).2.1.1.2 Under a pupillary diamater of 4mmGroup A:Corneal SA-RMS,TC-RMS,TT-RMS under a pupillary diamater of 4mm before surgery was compared with that one day after surgery,one week after surgery,and one month after surgery,there was no significant difference between the groups(P>0.05).Corneal tHOA-RMS under a pupillary diamater of 4mm before surgery was compared with that one day after surgery was significant difference between the groups(P<0.05).Corneal tHOA-RMS under a pupillary diamater of 4mm before surgery was compared with that one week after surgery,and one month after surgery,there was no significant difference between the groups(P>0.05).Group B:Corneal SA-RMS,tHOA-RMS,TC-RMS,TT-RMS under a pupillary dianater of 4mm before surgery was compared with that one day after surgery,one week after surgery,and one month after surgery,there was no significant difference between the groups(P>0.05).2.1.2 Corneal high-order aberrations after surgeryThere was no significant difference in SA-RMS between the A and B groups under a pupillary diamater of 6mm after the one day after surgery,one week after surgery,and one month after surgery(P>0.05).There were no significant differences in SA-RMS,tHOA-RMS,TC-RMS and TT-RMS between the A and B groups under a pupillary diamater of 4mm after the one day after surgery,one week after surgery,and one month after surgery(P>0.05).2.2 Intraocular high-order aberrations after surgeryThere were no significant differences in tHOA-RMS,TC-RMS and TT-RMS between the A and B groups under a pupillary diamater of 4mm after the one day after surgery,one week after surgery,and one month after surgery(P>0.05).2.3 High-order aberrations of the whole eye2.3.1 High-order aberrations of the whole eye after surgeryThere was significant difference in SA-RMS between the A and B groups undera pupillary diamater of 6mm after the one day after surgery,one week after surgery,and one month after surgery(P<0.05).There were significant differences in SA-RMS,tHOA-RMS and TT-RMS between the A and B groups under a pupillary diamater of 4mm after the one day after surgery,one week after surgery,and one month after surgery(P<0.05).There was no significant differences in TC-RMS between the A and B groups under a pupillary diamater of 4mm after the one day after surgery,one week after surgery,and one month after surgery(P>0.05).2.3.2 The actual SA-RMS of the whole eye and the estimated SA-RMS of the whole eye after surgeryThere was no significant difference in the actual SA-RMS of the whole eye and the estimated SA-RMS of the whole eye under a pupillary diamater of 6mm after the one day after surgery,one week after surgery,and one month after surgery(P>0.05).3 MTF and SRUnder a pupillary diamater of 6mm after one day after surgery,one week after surgery,and one month after surgery,there was significant difference in SR between the A and B groups(P<0.05),there was significant difference in MTF between 5 and 25cpd(P<0.05),and there was no significant difference in MTF at 0cpd and between 30 and 60cpd(P>0.05).Under a pupillary diamater of 4mm after one day after surgery,one week after surgery,and one month after surgery,there was no significant difference in SR and MTF(P>0.05).Conclusions:1 UCVA and BCVA were significantly improved in patients after aspheric IOL implantation.2 Micro-incision phacoemulsification and intraocular lens implantation resulted in less corneal damage and surgery did not significantly affect high-order aberrations on the corneal surface.3 Although there was no significant difference in MTF and SR between the aspherical IOLs with different SAs and the randomly implanted aspheric IOLs at the small pupil diameter,the postoperative SA-RMS,tHOA-RMS and TT-RMS were smaller of the aspherical IOL group with different SAs.There was a difference in MTF,SR and SA-RMS between the two groups at the large pupil diameter.Personalized selection of aspherical IOL groups implanted with different SAs,MTF,SR are larger and the SA-RMS is closer to the ideal value.It means that personalized selection of IOL implanted can provide better visual quality.4 If the OPD-Scanlll Optical Vision Quality Analyzer was used before surgery to measure high-order aberrations of the cornea to guide individualized selection of aspherical IOL with different SA.The estimated SA-RMS of the whole eye can be achieved after operation and a better visual quality can be achieved after surgery.
Keywords/Search Tags:aspheric IOL, Wavefront aberration, cataract, OPD-Scanlll Optical Vision Quality Analyzer
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