Tcm Syndrome Differentiation Of Chronic Obstructive Pulmonary Disease And Its Relationship With Pulmonary Function

Objective:By collecting the medical records of patients with chronic obstructive pulmonary disease,analyzing and sorting out the data,the syndrome types of chronic obstructive pulmonary disease were induced,and the correlation between TCM Syndrome types of COPD and lung function was discussed,to provide an objective basis for further guiding clinical differentiation and treatment.Methods:A cross-sectional study was conducted to analyze the clinical data of patients with chronic obstructive pulmonary disease?COPD?from October 2018 to January 2020 in the cough clinic and Pulmonary Department of the Affiliated Hospital of Shanxi University of Traditional Chinese medicine,it mainly includes the patient's name,sex,age,personal history and four diagnostic information of traditional Chinese medicine as well as lung function indexes,and uses statistical methods such as frequency analysis,cluster analysis,PCA and non-parametric test,the General Information,symptoms,syndrome differentiation and their relationship with pulmonary function were analyzed.Results:1.By analyzing the basic information of patients,341 patients with chronic obstructive pulmonary disease were included and 527 visits were made.Among the 341patients,the minimum age was 33 years old and the maximum age was 81 years old,the average age was 58 years old,and the prevalence of the disease ranged from 60 years old to 69 years old.There were 198 males and 142 females,and most of them were males,they accounted for 54.8%of the total number of cases,and 178 cases of drinking,accounting for 52.2%of the total number of cases.2.Distribution of TCM four diagnostic information of chronic obstructive pulmonary disease:?1?the common symptoms of respiratory tract are:cough,cough with sputum,wheezing,shortness of breath,progressive dyspnea,white sputum,easy-to-cough,sputum volume,thick sputum,heavy sputum,dyspnea,breathing in the throat,foam sputum,yellow sputum,dry cough without phlegm,expectoration.Sentence is too long,please supply a shorter sentence.?3?the tongue and pulse are arranged in order from more to less:Thick fur,White Fur,red tongue color,light red tongue color,slippery fur,thin fur,Pale tongue color,greasy rot fur,peeling fur,little fur,purple or dark tongue color,yellow fur,no fur,thin pulse,slippery,weak pulse,pulse number,slow pulse,deep pulse,astringent pulse,tight pulse,floating pulse.3.Main symptoms:cough,cough with Phlegm,dark complexion,cyanosis of lips,foam sputum,skin purple spot,dark or Purple Tongue,thin fur,and astringent pulse.Secondary symptoms:chest pain,chest suffocation,chest pain refused to press or tenderness.Through cluster analysis and PCA principal component analysis of the four TCM diagnosis information collected from patients with chronic obstructive pulmonary disease,a total of 6 TCM syndrome types were obtained.The names of each syndrome type and primary and secondary diseases are as follows:Phlegm-heat stagnation of Lung Syndrome:main symptoms:Sticky Phlegm,Yellow Phlegm,thirsty mouth,upset and irritable,dry or constipation,red tongue,greasy fur,yellow fur,pulse number.Secondary symptoms:Fever,Thick Moss,yellow urine.SYNDROME OF PHLEGM-DAMPNESS IN LUNG:Main Symptom:Phlegm quantity,sticky and greasy mouth or sweet mouth,slippery moss,slippery pulse,heavy head and body,White Phlegm,easy cough.Secondary Disease:Phlegm in the throat,Limb Edema,White Moss,pulse string.Syndrome of DEFICIENCY OF LUNG AND SPLEEN-QI:Main Disease:shortness of breath,tasteless mouth,abdominal distension,fatigue,easy to catch a cold,poor food intake,loose stools or diarrhea.Secondary disease:heavy pulse,slow pulse,sallow complexion,anxiety or depression.Syndrome of deficiency of lung and Kidney Qi:Main Symptom:aspiration difficulty,sitting up,mental fatigue,low voice,weak waist and knees,frequent urination at night,urinary incontinence;Secondary Symptom:Pale Face,Pale tongue,small pulse.Syndrome of deficiency of both lung and Kidney Qi and Yin:dry cough with little phlegm,spontaneous perspiration,night sweat,Little Moss,wheezing,dyspnea if moving,palpitation of heart,headache and Tinnitus.Secondary symptoms:Pharynx Dry Pharyngodynia,peeling fur,Pale red tongue,weak pulse.4.The relationship between lung function and different types of TCM syndrome differentiation:?1?relationship between lung function indicators of different TCM syndromes:the comparison of lung function indicators of six syndromes shows that there is no statistical significance in the difference between FVC%and fev₁%and FEV₁/FVC%of phlegm-heat stagnation syndrome and phlegm-dampness accumulation syndrome?p>0.05?.Lungs kidney Yin deficiency syndrome in patients with FEV₁%,FEV₁/FVC%than phlegm stasis resistance pulmonary lung syndrome,phlegm heat,phlegm wet yun yu lung syndrome,lung spleen deficiency syndrome and lung and kidney deficiency syndrome?p<0.05?,lung syndrome in patients with phlegm and blood stasis resistance FEV₁%,FEV₁/FVC%than phlegm wet aggregates lung syndrome,phlegm yu lung heat syndrome?p<0.05?,lung and kidney deficiency syndrome FEV₁%,FEV₁/FVC%below lung spleen deficiency syndrome.?2?different TCM syndrome types of lung function classification relationship:in 527 cases of medical records,?level,121 cases?23.0%?,lung function?level,133 cases?25.2%?,grade?,136 cases?25.8%?,grade?137 cases,accounting for 26%.In lung syndrome,phlegm and blood stasis resistance?level,19 cases?15.7%?,lung function?level,21 cases?15.8%?,grade?,23 cases?16.9%?,?level,24 cases?17.5%?;In phlegm yu lung heat syndrome,lung function?,30 cases?24.8%?,?level,25 cases?18.8%?,grade?,22 cases?16.2%?,?level,15cases?10.9%?;In phlegm wet aggregates lung syndrome,lung function?level,26 cases?21.5%?,grade?,22 cases?16.5%?,grade?,19 cases?14.0%?,grade?,16 cases?11.7%?;In the lung spleen deficiency syndrome,lung function?level,17 cases?14.0%?,grade?,25 cases?18.8%?,grade?,26 cases?19.1%?,?level,27 cases?19.7%?;In the lung and kidney deficiency syndrome,lung function?level,15 cases?12.4%?,?level,21 cases?15.8%?,grade?,24 cases?17.6%?,grade?29 cases?21.2%?,In the lungs kidney Yin deficiency syndrome,lung function?level,14 cases?11.6%?,grade?,19 cases?14.3%?,grade?,22 cases?16.2%?,grade?,26 cases?19.0%?.Conclusion:1.TCM syndrome differentiation:through cluster analysis and PCA principal component analysis,6 TCM syndrome types were identified,which were phlegm-stasis syndrome,phlegm-heat stagnation syndrome,phlegm-dampness accumulation syndrome,deficiency of lung-qi syndrome,deficiency of lung-kidney qi syndrome,and deficiency of lung-kidney qi and Yin syndrome,respectively.2.Through statistical analysis of the relationship between TCM syndrome type and lung function,the results show that there is a certain correlation between lung function and TCM syndrome type.To some extent,lung function index can be used as a reference index for clinical TCM syndrome differentiation and classification of chronic obstructive pulmonary disease,which opens a new idea for TCM syndrome differentiation and treatment of COPD.