Analysis Of The Time And Factors Affecting The Conversion Of Smear Positive Pulmonary Tuberculosis Patients In Aksu Area

Objective:To investigate the impacting factors on treating pulmonary tuberculosis patients with initial smear-positive Method:A total of 152 patients with initial smear-positive pulmonary tuberculosis were treated with HRZE regimen for 2 months.Kaplan-meier method was used to calculate sputum conversion rate.X~2test was used for single factor analysis,and Cox regression model was used for multivariate analysis to explore the influencing factors.Result:After 2 months treatment,the conversion rate for smear-negative was 75.7%.Univariate analysis showed that there was a statistically significant difference between occupational(farmers vs others),lesion range,bronchial tuberculosis,and bacterial load of sputum between the two months of negative conversion rate(p<0.05),and there was no statistically significant difference with age and gender factors;multivariate analysis showed that the influencing factors were occupation(farmers)and the amount of bacteria in the initial diagnosis.Conclusion:For newly treated smear positive pulmonary tuberculosis patients,the bacterial count and occupation(farmers)at the time of initial diagnosis is the main factor that affects the sputum conversion to negative for 2 months of regular anti-tuberculosis treatment,and it should be paid attention to in the prevention and treatment of tuberculosis.