Comparison Of The Efficacy Of Posterior Intervertebral Autologous Bone And Allogeneic Bone Implantation In The Treatment Of Lumbar Brucellar Spondylitis

Objective: To compare the safety,feasibility and clinical efficacy of posterior intervertebral autologous bone and allogeneic bone implantation in the treatment of lumbar brucellar spondylitis.Methods: Retrospective analysis was performed on the clinical records of 43 patients who received simple posterior surgery in our hospital from August 2010 to August 2015.Divided into autologous bone group(28 cases)and allogeneic bone group(15 cases).compare the data of the two groups before and after surgery and at the last follow-up.Erythrocyte sedimentation rate(ESR),C-reactive protein(CRP),serum tube agglutination test(SAT),visual analogue scale(VAS)score,low back pain(Oswestry Disability Index ODI)score,Frankel spinal cord injury grade,The height of intervertebral space,Vertebral fusion rate in each groups were analyzed.Results: All patients in the two groups completed the operation successfully.All patients were followed up for more than 36 months.There was no aggravation of nerve injury symptoms and recurrence of infection.There was no subside or malposition bone graft,disruption of internal fixation.At the last follow-up,The effective improvement rate of FRANKEL classification in autogenous bone group(group A)was 84.61%(11/13),and that in allogenic bone group(group B)was 80%(4/5).The height of intervertebral space between autogenous bone group(group A)and allogeneic bone group(group B)was not statistically significant.At 12 months after operation,the fusion rate of both groups was100%.Conclusion: There was no significant difference in the clinical efficacy of autologous bone and allogeneic bone implants in the treatment of lumbar brucellar spondylitis.The safety and efficacy of the two are similar.Allogeneic bone can be an ideal substitute for autologous bone.