| Objective: The study according to analyze the prevalence and trends of gastric cancer in Xining and to discuss the clinicopathological characteristics of patients with gastric cancer in different ages,provided references for the local prevention and treatment of gastric cancer in public health system.Methods: 1.The study calculated the incidence and mortality of gastric cancer(gender,age,urban and rural)and calculated the changes of gender,age and death trend among different nationalities based on the data provided by the tumor registration of Xining Center for Diseases Control and Prevention,meanwhile the permanent residents of Xining as the research object.2.According to retrospectively analysis the clinical pathological data of 906 gastric cancer patients diagnosed by the Affiliated Hospital of Qinghai University,the People's Hospital of Qinghai Province and the Red Cross Hospital of Qinghai Province from 2015 to 2017,and compared the clinicopathological features of patients with gastric cancer at different ages.Results: 1.There were 4,822 new cases of gastric cancer from 2009 and 2016.conclude 3,583 males and 1,239 females.2,290 cases in villages and 2,532 in towns.The morbidity of males(38.37/100,000 years)was higher than females(13.35/100,000 years),and the ratio was about 2.9.Similar,in rural areas(39.29 per 100,000 years)was higher than that in urban areas(20.59 per 100,000 years),accounting for about 1.9 to 1;From 2009 to 2016,there were 2109 gastric cancer deaths,1,543 in males and 566 in females.There were 1,185 cases in villages and 924 in cities.Male mortality(16.64 per 100,000 years)was higher than female mortality(6.42 per 100,000 years),which was 2.6:1.The mortality rate in rural areas(20.4 per 100,000 years)was higher than that in urban areas(762 per 100,000 years),a ratio of 2.7 :1;The morbidity and mortality overall are on the rise.2.From 2009 to 2016,there were 4,822 new cases of gastric cancer in Xining,among which 3,561 cases were of the Han nationality,accounting for 73.8%;the Hui nationality was 639 cases,accounting for 13.2%;456 Tibetans,accounting for 9%,and other 166 cases,the ratio is 4%.Incidence rate: Han(29.33/100,000),Hui(24.21/100,000),Tibetan(51.12/100,000);Mortality: Han(14.83/100,000),Hui(8.13/100,000),Tibetan(8.59/)100,000).During this decade,the incidence and mortality of gastric cancer were on the rise,with Tibetan significantly higher than other ethnic minorities.3.There were 96 cases in the youth group,accounting for 10.6%;and 724 cases in the middle and elderly group,accounting for 80%;the elderly group,86 cases,accounting for 9.4%.There were statistically significant differences in gender,ethnicity,HP infection,site of onset and pathological type among the three groups.The patients were more likely to suffer from gastric cancer is generally 45-74 years old,with the ratio of male to female(2.9:1),in which the proportion of young gastric cancer patients is higher than that of men,the location of incidence is mainly the gastric body and gastric sinus,the middle and old age are mainly cardia and gastric sinus,and the pathological type of young patients is mainly poorly differentiated adenocarcinoma.Conclusion: 1.The morbidity and mortality of gastric cancer was increasing in Xining between 2009 and 2016.Men are superior to women;The country is superior to the city.2.Gastric cancer patients Characteristics of morbidity and mortality of Xining have obvious difference among different nationality.The incidence rate of Tibetan is significantly higher than that of the Han and the Hui nationality,and the mortality rate of Han is higher than the other two groups.Men are significantly higher than women,the high incidence of age for the elderly.Therefore,cancer screening in the elderly is more important,especially in the Tibetan population.3.Gastric cancer mainly occurs in middle-aged and elderly male patients,mainly in poorly differentiated adenocarcinoma,mostly in the cardia and gastric sinus;In young gastric cancer patients,women account for a relatively high proportion.And the lesion site is mainly the gastric body and gastric sinus,with poorly differentiation degree.Signet ring cell carcinoma was more common than other age groups and its clinical stage was later. |
PDF Full Text Request