Analysis Of Relationship Between Liver Qi Stagnation Syndrome,Phlegm-blood Stasis Syndrome And Clinicopathological Characteristics In Patients With Papillary Thyroid Carcinoma

Objective:To explore the relationship between liver qi stagnation syndrome,phlegm-blood sta sis syndrome and clinicopathological characteristics in patients with Papillary Thyroid Carcinoma,and to clarify the difference of clinicopathological characteristics between li ver qi stagnation syndrome and phlegm-blood stasis syndrome in patients with Papillar y Thyroid Carcinoma.It provides a new direction and reference for the diagnosis of Pa pillary Thyroid Carcinoma.Methods:From March 2018 to December 2018,121 patients with Papillary Thyroid Carcinoma were admitted to the Department of Thyroid.vein.Hernia surgery,Second People's Hospital Affiliated to Fujian University of Traditional Chinese Medicine.Before surgery,Chinese syndrome differentiation classification was liver qi stagnation syndrome or phlegm-blood stasis syndrome.The data of sex,age,thyroid function,ultrasonic appearance,maximum diameter of tumors,volume,capsular invasion,number of tumors,aspect ratio,calcification,lymph node metastasis,Ki67 and the TNM stage were collected.SPSS20.0 statistical software was used to analyze and compare the data,and to observe its correlation with liver qi stagnation syndrome,phlegm-blood stasis syndrome.Results:1.121 cases of papillary thyroid carcinoma in this study,57 cases of liver qi stag nation syndrome,64 cases of phlegm-blood stasis syndrome,of which 30 cases were m ales,accounting for 24.8%,91 cases were females,accounting for 75.2%,most of the p atients were female.2.There was no significant difference in age,gender and thyroid function between liver qi stagnation syndrome and phlegm-blood stasis syndrome(P>0.05).3.There were significant differences in aspect ratio,calcification and maximum di ameter between The liver qi stagnation syndrome and The phlegm-blood stasis syndro me(P<0.05),The majority of phlegm-blood stasis syndrome is the aspect ratio >1,calci fication,the maximum diameter >1cm.The liver qi stagnation syndrome is more commo n in the aspect ratio >1 or <1,and the maximum diameter is ?1cm.4.There were significant differences in the volume of tumors between The liver q i stagnation syndrome and The phlegm-blood stasis syndrome(P<0.05).The volume of tumors in The phlegm-blood stasis syndrome was larger than The liver qi stagnation s yndrome.5.There was no significant difference in the number of tumors between The liver qi stagnation syndrome and The phlegm-blood stasis syndrome(P>0.05).There were si gnificant differences in lymph node metastasis and Ki67(P<0.05).phlegm-blood stasis syndrome group is more common in Lymph node metastasis,The liver qi stagnation sy ndrome group is more common in Single focus and Ki67<5%.Compared with The live r qi stagnation syndrome,the incidence of multifocality was higher in The phlegm-bloo d stasis syndrome group(25/64).6.In this study,97 cases were found in stage I,15 cases in stage II,9 cases in stage III and 0 cases in stage IV,of which stage I was the main stage,accounting for 80.16%.There was no significant difference in TNM stage between liver qi stagnation syndrome and phlegm-blood stasis syndrome(P> 0.05).Conclusion:There are some relationships between liver qi stagnation syndrome,phlegm-blood s tasis syndrome and the maximum diameter,volume,aspect ratio,calcification,number of tumors,lymph node metastasis and Ki67.The liver qi stagnation syndrome in patients with PTC is more common in Single focus and Ki67 < 5%,The phlegm-blood stasis s yndrome in patients with PTC is more common in the maximum diameter > 1 cm,as pect ratio>1,calcification,lymph node metastasis.Patients with phlegm-blood stasis syndr ome may have a tendency of lymph node metastasis.So,more careful examination to ly mph node metastasis is needed.