Difference Between Rome ? And Rome ? Criteria In Diagnosis Of Functional Dyspepsia

Objective: To compare the difference between Rome ? and Rome ? criteria in diagnosis of functional dyspepsia(FD),and to provide references for the clinical application of Rome ? criteria.Methods: Patients admitted to hospital because of dyspeptic symptoms were continuously collected in this study,and we carried out a questionnaire investigation by using Rome ? and Rome ? Diagnostic Questionnaires.Then the diagnosis of FD was Performed according to Rome ? and Rome ? criteria,respectively.The diagnosis rate,symptom distribution,severity and subtype ratio were compare between Rome ? and Rome ? criteria.The difference of diagnosis rate between the two criteria was analyzed.Results:(1)Of the 107 FD patients,66.36% and 87.85% patients were consistent with Rome ? and Rome ? criteria for FD respectively,and 61.68% patients were consistent with both Rome ? and Rome ? criteria for FD.The diagnosis rates of FD was statistically significant difference between the two criteria(P<0.001).(2)Compared with Rome ? criteria,the incidence of postprandial fullness was significantly lower in FD patients and male FD patients diagnosed by Rome ? criteria(P<0.05).male FD patients diagnosed by both Rome ? and Rome ? criteria had higher incidence of heartburn symptom than female FD patients(P<0.05).(3)There was statistically significant difference in the FD subtype composition ratio between patients diagnosed by Rome ? criteria and patients diagnosed by Rome ? criteria(P < 0.001),The Rome ? criteria had a higher epigastric pain syndrome(EPS)composition ratio and subtype overlap rate.Conclusion: Patients diagnosed by Rome ? criteria have relatively higher diagnosis rate of FD and EPS subtype composition ratio than those diagnosed by Rome ? criteria.Rome ? criteria emphasize more on symptom severity and outbreak frequency.The Rome ? criteria are simpler to operate,more conducive to clinical practice and scientific research,and more consistent with the clinical features of FD.