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The Empirical Research Of Risk Factors And The Effect Of Exercise Intervention For Irritable Bowel Syndrome Patients Based On The Rome ? Criteria

Posted on:2020-07-29Degree:DoctorType:Dissertation
Country:ChinaCandidate:C L ZhouFull Text:PDF
GTID:1364330575481122Subject:Nursing
Abstract/Summary:PDF Full Text Request
Irritable bowel syndrome(IBS)is the most common functional gastrointestinal disease.It has the characteristics of long course,easy to repeat,severe symptoms,light signs,difficult to check and so on.The incidence is increasing year by year.Although irritable bowel syndrome will not cause disability or death,it will bring direct or indirect social and psychological pressure and heavy medical and economic burden to patients.In order to specifically identify the occurrence and development of irritable bowel syndrome and avoid overlapping with other functional gastrointestinal diseases,the Rome Commission simplified and precisely the intestinal symptoms and onset time based on the widely used Rome III standard in 2016,and revised the Rome ? standard to become the latest gold standard for the diagnosis of irritable bowel syndrome.The standard diagnosis of irritable bowel syndrome has rarely been reported.Irritable bowel syndrome is often targeted at the main or most serious symptoms,but the condition of IBS is complex and the treatment is not completely effective.Drug intervention for IBS has many limitations,such as uncertain efficacy,long course of treatment,and many side effects.More and more attention has been paid to non-drug interventions in IBS,and its prospects have become the main effective measures to prevent and treat IBS.Among them,sports have been paid more and more attention by scholars.Previous studies on interventions for patients with irritable bowel syndrome were usually randomized controlled trials,but studies have shown that only 14% of the evidence obtained by RCT can be widely used in clinical practice after an average of 17 years.Therefore,from the perspective of research efficiency and cost,RCT has obvious shortcomings.The results are not conducive to the transformation to practice.It has poor external effectiveness and can not provide direct evidence for clinical use.With the demand for evidence,researchers pay more and more attention to empirical research research.Researchers need the studies of the selection of treatment measures according to patients' actual conditions and willingness in a real environment.It is an extension and important supplement of the traditional randomized controlled trial study and provides direct evidence that can be used clinically.Therefore,this study will explore the applicability of the Roman ? standard to the IBS population in China.Firstly,evidence-based methods are used to search for evidence of the use of the Roman ? standard.Secondly,real-world studies are used to verify the application of the Roman ? standard in order to realize the transformation of evidence into practice.To clarify the real intervention effect of exercise on irritable bowel syndrome patients under the new diagnostic criteria,and to provide theoretical and experimental basis for reducing the harm of irritable bowel syndrome and improving the quality of life of patients.Objective:In order to explore the applicability of Rome ? diagnostic criteria in China,we firstly use Rome ? as diagnostic criteria to evaluate the risk factors affecting IBS patients and provide theoretical and experimental basis for effective intervention;secondly,we search for theoretical evidence of the effect of exercise intervention on IBS patients through evidence-based methods;thirdly,we realize the transformation from theory to practice through empirical research.To clarify the real intervention effect of exercise on irritable bowel syndrome patients under the new diagnostic criteria.Methods:1.Using convenient sampling method,Changchun City was selected as the research site to carry out a questionnaire survey on the risk factors of irritable bowel syndrome.2.Evidence-based medicine(EBM)was used to search Pubmed,Medicine,Embase,Cochrane,China HowNet,Wanfang database and Chinese biomedical literature database to systematically evaluate the effect of exercise intervention on patients with irritable bowel syndrome.3.Recruitment of patients with irritable bowel syndrome who participated in the questionnaire survey and met the Rome ? criteria,subject to the examination and informed consent of the Ethics Committee.According to the order of incorporation,the number was numbered and randomly grouped by computer-generated random number table.The empirical research design was used to validate the outcomes of exercise intervention on the severity of symptoms,anxiety,depression,quality of life and life satisfaction of patients with irritable bowel syndrome.Results:1.Cross-sectional survey results showed that the prevalence of irritable bowel syndrome was 18.1% according to Rome III standard,which was about 3/4 of Rome III standard.Sports time(<2h/w),history of intestinal infection and anxiety were independent risk factors for the occurrence of irritable bowel syndrome(Rome ? standard).Dietary factors,history of intestinal infection and anxiety were independent risk factors for IBS(Rome III standard).2.Systematic evaluation of the effect of exercise intervention on patients with irritable bowel syndrome showed that 329 articles were searched and 14 randomized controlled trials were screened,totaling 683 patients.In the 14 studies,the forms of sports include different types of yoga intervention,sports,Taiji,mountain climbing,Baduan Jinqigong and other different sports.The results showed that in patients with irritable bowel syndrome,exercise nursing intervention improved the intestinal symptoms,quality of life,mental state and other outcome indicators better than routine nursing or maintenance of previous lifestyle,and clarified the effect of exercise nursing on patients with irritable bowel syndrome.3.Real-world results showed that: Exercise intervention can effectively alleviate the severity of symptoms in patients with irritable bowel syndrome(P < 0.01).Exercise intervention can effectively reduce the severity of irritable bowel syndrome(P < 0.01),including the degree of abdominal pain(P < 0.01),the frequency of abdominal pain(P < 0.01),the degree of abdominal distension(P < 0.05),the defecation satisfaction score(P < 0.05).After intervention,the life impact score of the experimental group was lower than that of the control group(P < 0.01).4After intervention,the depression score of the experimental group was significantly lower than that of the control group(P < 0.01),and the depression score of the experimental group was significantly lower(P < 0.01),which was also significantly different from that of the control group(P < 0.01).After intervention,the total score of IBS-QOL was significantly higher than that of the control group(P < 0.05),and the quality of life was significantly improved.In all dimensions,the intervention group was significantly higher than the control group in anxiety,behavioral disorders,physical thoughts,food evasion and social function(P < 0.05);there was no significant difference in health concerns,sexual behavior and interpersonal relationships between the two groups.The results of life satisfaction showed that after intervention,the total score of life satisfaction in the experimental group was higher than that in the control group(P < 0.05),which proved that the life satisfaction of the experimental group had been significantly improved.In all dimensions,the three dimensions of wish fulfillment,self-evaluation and mood state improved significantly better than that of the control group(P < 0.05),and there was no difference in other dimensions.Conclusions:1.The results of this study showed that: with the reference of Rome III standard,sports time(<2h/w)was found to be an independent risk factor for the occurrence of irritable bowel syndrome under Rome ? standard,and sports time(<2h/w)was an independent risk factor for the occurrence of irritable bowel syndrome,which provided practical evidence for sports intervention in patients with irritable bowel syndrome under Rome ? standard.2.Systematic evaluation of the effect of exercise intervention on IBS patients shows that exercise therapy is beneficial to IBS patients.This provides theoretical evidence for us to explore the effect of exercise intervention on IBS patients in the real world.3.Using pragmatical research design and based on empirical research to explore the impact of exercise on IBS patients,the results show that exercise can effectively improve symptoms and quality of life,alleviate anxiety,depression and improve life satisfaction of patients.4.To sum up,as a nursing intervention mode of IBS,exercise intervention can improve abdominal symptoms,alleviate anxiety and depression,improve quality of life,and increase life satisfaction.It has the characteristics of economy and convenience.It is a suitable intervention measure for general promotion.
Keywords/Search Tags:Irritable Bowel Syndrome, Rome ? criteria, Risk Factor, Exercise, Empirical research
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