Relationship Between Tea Drinking And Glucose Metabolism In Middle-aged And Elderly Individuals

Objective To analyze the status of tea drinking,glucose metabolism and gender difference in middle-aged and elderly individuals,and to explore the relationship between tea drinking and glucose metabolism.Methods Residents who were eligible for study by using the Lanzhou data of “REACTION" study.We extracted relevant data from questionnaire surveys,physical examinations and laboratory tests.The study subjects were divided into three groups according to the frequency of tea drinking: non-drinkers,occasional tea drinkers and regular tea drinkers.Non-drinkers were set as the control group and the tea drinking quantity of regular tea drinkers was divided into 3 groups by 0-5g/day,5-10g/day and 10g/day.The tea drinking years were divided into 3 groups by 0-20 years,20-40 years and 40 years.The correlation between different tea drinking indicators and different glucose metabolism states was discussed by using logistic regression analysis.Results(1)There were 8012 subjects which had 2209 males(27.6%)and 5803 females(72.4%).The average FPG,2hPG and HbA1 c were(5.98±1.71)mmol/L,(8.67±3.93)mmol/L,(6.16±1.03)%.The prevalence of IGR and DM were 28.1% and 27.5%,respectively.The prevalence of DM in males was higher than that in females(34.0% vs 25.1%,P<0.05).(2)There were 2390 cases(29.8%)of regular tea drinkers and male was higher than that of female(54.8% vs 20.3%,P<0.001).There were 2,793(34.9%)cases of occasional drinkers and 2829 cases(35.3%)of non-drinkers and the number of male tea drinkers was lower than that of female(27.8% vs 37.6%;17.4% vs 42.1%,all P<0.001).(3)Non-drinkers were set as the reference group,tea drinkers had higher levels of FPG,SBP,DBP,BMI,WHR,smoking,drinking,hypertensio(all P <0.05).With the increase of the frequency,years and amount of tea drinking,the lever of FPG,SBP,DBP,BMI,WHR were increased(all P <0.05).(4)Compared with the group of normal glucose tolerance,the proportion of regular tea drinkers,and tea drinking more than 40 years and consumption more than 10g/d in DM was high(2.3% vs 29.1%;4.3% vs 2.8%;5.7% vs 2.8%,all P<0.05).(5)Compared with non-drinkers,regular tea drinkers,age limit more than 40 years and consumption more than 10g/d had higher prevalence of DM(29.7% vs 27.0%;39.0% vs 27.0%;37.1% vs 27.0%,all P<0.05).With the increase of consumption amount and years of tea,the prevalence of male abnormal glucose metabolism increased and decreased in female(all P<0.05).(6)Binary logistic regression analysis showed that after adjusting age and confounding factors,regular tea drinking,years and quantity was positively correlated with the risk of IGR in males(all P<0.05).And there was a negative correlation between regular tea drinking,years,quantity and female IGR risk(all P<0.05).(7)Binary logistic regression analysis showed that after adjusting age and confounding factors,there was a positive correlation between the risk of DM in males with regular tea drinking,years and quantity(all P<0.05).Regular tea drinking,years and quantity was negative correlated with the risk of DM in females(all P<0.05).Conclusion Regular tea drinking is correlated with IGR and DM,and there may be differences between different genders.