Changes Of The T Cells Immune Function In Apoplexy Yang Syndrome And Mechanism Of Xingnaojing Treatment

?Purpose?1?To evaluate the changes of the T lymphocyte immune function in patients with apoplexy Yang syndrome,and to provide objective evidence for syndrome differentiation of apoplexy Yang syndrome;2?Observe brain after intravenous injection therapy for stroke Yang shut the T lymphocyte level changes,and assess the state of nerve function defect,revealing the refreshing static injection can be adjusted by T lymphocyte immune function,improve nerve function defect,and to achieve the effect of treating stroke Yang close your card,to extend the pathogenesis of stroke Yang shut the research and clinical medicine to provide new research direction.?Method?The Thirty-six healthy patients and thirty-six patients hospitalized in the department of neurology of jiangxi provincial people's hospital due to stroke were selected.Meanwhile,they met the diagnostic criteria of stroke Yang shuan in traditional Chinese medicine and ischemic stroke in western medicine.Healthy people were included in the control group,and stroke Yang shuan was included in the observation group.The observation group was treated with xingnaojing injection in accordance with the guidelines for the diagnosis and treatment of ischemic stroke.The CD4~+T%,CD8~+T%,CD4~+T/CD8~+T ratio and NIHSS score of 16 patients in the observation group were collected after3 days and 7 days of treatment.SPSS22.0 was used for data statistics..?Result?1?Comparison of indicators between control group and observation group:There were statistically significant differences between the control group and the observation group(P<0.05).2?Comparison of indicators between the observation group before treatment and 3 days after treatment:There was no significant difference in CD4~+T%,CD8~+T%(P>0.05)and CD4~+T/CD8~+T ratio in the observation group after 3 days of treatment(P<0.05).The NIHSS score of the observation group was significantly different after 3 days of treatment(P<0.05).3?Comparison of indicators between the observation group before treatment and 7 days after treatment:There were significant differences in the CD4~+T%,CD8~+T%and CD4~+T/CD8~+T ratios in the observation group after 7 days of treatment(P<0.05).There was a significant difference in the NIHSS score of the observation group after 7 days of treatment(P<0.05).?In conclusion?1?The decrease of CD4+T%,CD8+T%and CD4+T/CD8+T ratio can be used as one of the objective evidences for syndrome differentiation of apoplexy Yang syndrome.2?Xingnaojing injection can effectively improve the neurological defects of patients with apoplexy syndrome after 3 days,and increase the ratio of CD4~+T%,CD8~+T%and CD4~+T/CD8~+T after 7 days,showing obvious clinical efficacy.3?Xingnaojing injection can improve the immune function by adjusting the ratio of CD4~+T%,CD8~+T%and CD4~+T/CD8~+T,and exert its effect on the patients with apoplexy syndrome.