The Effect Of Hip Hypertension In Pregnancy On Long-Term Blood Pressure In Postpartum Women

Objectives The data of pregnancy and health examination of female workers in Kailuan were analyzed,to investigate the effect of hip hypertension in pregnancy(HIP)on longterm blood pressure in postpartum women.Methods A total of 4331 females whose age among 30 to 60 gave birth in Kailuan group hospital during the period between October 1976 to December 2014 and participated in physical examination from 2006 to 2014,exclusion of pre-pregnancy history of hypertension,delivery after physical examination and absence of systolic blood pressure or diastolic blood pressure at physical examination,eventually 4072 cases were included in the retrospective cohort study.Participants were divided into HIP(n=602)and NHIP(n=3470)group by the history of HIP,comparing the incidence of hypertension during the physical examination from 2006 to 2014.Linear regression and multivariate Logistic regression were used to analyze the effect of HIP on long-term blood pressure in postpartum women.Results After an average follow-up of 17.17 years,a total of 789 cases(1.13/100 personyears)of hypertension were detected in 4072 subjects,including 589 cases(1.02/100person-years)in NHIP group and 200 cases(1.64/100 person-years)in HIP group.In the overall objects of observation,linear regression analysis showed that HIP was associated with an estimated increase in long-term systolic blood pressure of 4.37 mm Hg and diastolic blood pressure of 2.63 mm Hg.And multivariate Logistic regression analysis showed that the risk of long-term hypertension in HIP group was 34% higher than that in NHIP group after adjusting for other risk factors.However,the analysis of different age groups found that HIP was associated with an estimated increase in systolic blood pressure of 4.17,3.81 mm Hg and diastolic blood pressure of 3.08,2.49 mm Hg on 30~ <40 and40~ <50 years old women,respectively.Multivariate Logistic regression analysis showed that the risk of hypertension in HIP group was higher than that in NHIP group,and RR(95%CI)were 2.06(1.35~3.16)?1.45(1.16~1.81)?1.23(1.01~1.50)on 30~ <40,40~ <50,and 50~60 years old women,respectively.Conclusions Compared with NHIP women,the incidence of long-term hypertension increases in women with HIP after delivery.HIP is a risk factor for long-term hypertension in women after delivery.For the women aged from 30~60,the risk of longterm hypertension gradually decreased with the increase of age in HIP women.However,it was only statistically significant when the subjects aged from 30~ <50 years old,that long-term systolic blood pressure and diastolic blood pressure gradually decreased with the increase of age in HIP women.Figure 0;Table 6;Reference 107...