Research On Application Of Angioplasty And Replacement In Radical Resection Of Non-small Cell Lung Cancer

Objective: To explore the safety and efficacy of pulmonary angioplasty in the treatment of non-small cell lung cancer.Summary of surgical techniques and perioperative management and related complications.Methods:Retrospective statistical analysis was conducted to collect the clinical data of patients with non-small cell lung cancer who visited our department from April 2013 to April 2018.They were divided into pulmonary angioplasty group(220 cases)and total pneumonectomy group(235 cases).Results:There was no significant difference in preoperative general data between pulmonary angioplasty group and total pneumonectomy group.In the pulmonary angioplasty group,86 cases had postoperative complications,3 cases died of pulmonary embolism,anastomotic leakage and heart failure.The rest were cured and discharged after conservative treatment.In the total pneumonectomy group,114 cases had postoperative complications and 9 cases died.The causes were respiratory failure,heart failure and anastomotic leakage.The rest patients were cured and discharged after symptomatic treatment.The incidence of postoperative complications in pulmonary artery plasty group was lower than that in total pneumonectomy group,and the hospitalization time was shorter,P < 0.05.The difference was statistically significant.Postoperative follow-up results showed that the KPS score of pulmonary angioplasty group was higher,suggesting that the quality of life after operation was better,and there was statistical difference(P < 0.01).The survival rate of the two groups showed a downward trend,and the pulmonary angioplasty group could achieve the same therapeutic effect as the total pneumonectomy group.Conclusion: The operation of pulmonary angioplasty is more difficult than total pneumonectomy.The risk of bleeding and operation time will increase,but the incidence of complications and perioperative mortality can be effectively reduced.The quality of life of the patients after pneumonectomy is higher than that after pneumonectomy.Pulmonary angioplasty is safe and effective in the treatment of non-small cell lung cancer involving pulmonary artery trunk.Objective:To study the safety and efficacy of pulmonary vein angioplasty in the treatment of non-small cell lung cancer.Summarize surgical techniques and control measures for perioperative management and related complications.Methods: Retrospective statistical analysis of the clinical data of patients with non-small cell lung cancer in our department from April 2013 to April 2018.According to the surgical methods,the patients were divided into pulmonary venoplasty group and total pneumonectomy group,including 11 cases in pulmonary venoplasty group and 235 cases in total pneumonectomy group.Results:There was no significant difference in preoperative general data between pulmonary venoplasty group and total pneumonectomy group.In the pulmonary venoplasty group,6 cases had postoperative complications,all of which were treated conservatively without death.There were 114 complications and 9 deaths in total pneumonectomy group.The causes included respiratory failure,heart failure and anastomotic fistula.The other cases were cured after conservative treatment and discharged.The incidence of complications after operation was higher than that of the former.The difference was statistically significant.All patients with pulmonary venoplasty had follow-up records.217 patients in total pneumonectomy group were followed up effectively.Higher KPS score in pulmonary venoplasty group indicated better quality of life after operation,and there was statistical difference(P < 0.05).The survival rate of the two groups decreased with time,and the pulmonary venoplasty group could achieve the same therapeutic effect as the total pneumonectomy group.Conclusion:The operation of pulmonary venoplasty is more difficult than total pneumonectomy.The risk of bleeding and operation time will increase,but this technique does not increase the incidence of complications and perioperative mortality.The quality of life of the patients after pneumonectomy is higher than that after pneumonectomy.Pulmonary venoplasty is of satisfactory clinical effect and can improve the therapeutic effect of non-small cell lung cancer.Objective: This study aims to summarize the clinical experience of superior vena cava replacement with artificial blood vessel and pulmonary artery replacement in our department,and to explore the clinical application value of artificial blood vessel.Methods:A retrospective study was conducted to analyze the clinical data of 10 patients with non-small cell lung cancer who underwent artificial vascular replacement from April2013 to April 2018 in our department.Among them,6 patients underwent superior vena cava replacement and 4 patients underwent pulmonary artery replacement.Results: There were no perioperative deaths in patients undergoing superior vascular replacement and pulmonary artery replacement.Postoperative complications such as arrhythmia,pulmonary infection,and wound infection were cured after symptomatic treatment.The effective survival of patients was significantly longer than that of unoperated patients.Conclusion: When patients with NSCLC have superior vena cava syndrome or long segment pulmonary artery invasion,it is feasible to perform superior vena cava replacement or pulmonary artery replacement.After resection of tumors and diseased blood vessels,artificial blood vessel reconstruction can provide conditions for further comprehensive treatment of NSCLC patients and is of clinical application value.