Analysis Of Risk Factors And Clinic Chara Cteristics Of Neonatal Hypoxic-ischemic E Ncephalopathy

Objective: To investigate the risk factors and clinical characterist ics of neonatal hypoxic-ischemic encephalopathy(HIE).Methods: The factors affecting the severity of HIE were investig ated by using a retrospectivre study.The Clinical data of patients dur ing January 2013 and December 2018 were collected,then T test,Chi-square test and logistic regression analysis were employed to analyse s the data to find the risk factors related to the severity of HIE.Results: A total of 68 neonates were enrolled including 36 mild cases and 32 moderate to severe cases.The result of univariate anal ysis shows that the number of days in hospital,amniotic fluid stain,int rauterine distress,nuchal cord,hearing screening is significant changing between mild and moderate to severe cases(p < 0.05).The univariat e analysis between 68 cases neonatal with HIE and 68 cases neonata l without HIE shows that the number of days in hospital,amniotic flu id stain,nuchal cord,intrauterine distress,gastrointestinal bleeding and he aring screening is significant changing between the two cases above(p < 0.05).Analysis the cases which have statistical difference in univariate analysis with logistic regression analysis.The result shows th at amniotic fluid stain(OR:1.164,95% CI:0.146,1.581,p<0.05),nuchal cord(OR:0.094,95% CI:0.015,0.578,p<0.05)and intraut erine distress(OR:0.215,95% CI:0.066,0.702,p < 0.05)are ind ependent risk factor who influences the severity of HIE;Amniotic flui d stain(OR:5.797,95% CI:2.137,15.723,p < 0.05),nuchal cord(OR:4.913,95% CI:2.009,12.016,p < 0.05)and intrauterine di stress(OR:21.711,95% CI:8.666,54.391,p < 0.05)are independ ent risk factor of HIE.Conclusion: Amniotic fluid stain,nuchal cord and intrauterine distr ess are independent risk factor of HIE in children with HIE.Amniotic fluid stain,nuchal cord and intrauterine distress are independent risk f actor who influences the severity of HIE.We should do preventive w ork in expected date.we should closely monitor the amniotic fluid stai n,nuchal cord,intrauterine distress of children with HIE.We should earl y predict the severity of HIE to avoid the occurrence of children wit h HIE,control the severity of the condition and to improve the recov ery of children.