Effect Of Delayed PCI At Different Time Windows On Short-term Prognosis Of Patients With Acute Myocardial Infarction

Background: Percutaneous coronary intervention(PCI)can rapidly open infarctrelated artery(IRA),restore blood perfusion of local myocardium,reduce the accumulation of harmful metabolic substances,and reduce myocardial cell damage.In particular,it has obvious advantages in reducing revascularization and cardiovascular events,and has become the treatment of choice for ST-segment elevation myocardial infarction(STEMI).Primary PCI required the opening of the IRA within 12 hours.Some STEMI patients missed the time window of primary PCI treatment due to technical and equipment requirements and delays in patient visits.Currently,the choice of delayed PCI treatment time for STEMI patients who missed primary PCI remains controversial.Objective: This study used STEMI patients who underwent delayed PCI in different time windows.Compare the short-term prognosis of patients,the aim is to provide a clinical basis for the selection of delayed PCI treatment time in STEMI patients.Methods: STEMI patients who underwent delayed PCI in the Department of Cardiology,First Affiliated Hospital of Henan University of Science and Technology from September 2015 to December 2017 were selected as subjects.According to the patient's onset time to the delayed PCI treatment time,the patients who met the criteria were divided into two groups: the short-term group(12h<PCI time?14 days);the longterm group(PCI time>14 days).The general clinical data and PCI results of the two groups were collected and statistically analyzed.Major adverse cardiovascular events(MACE)and clinical data were collected during the hospitalization and 6 months after surgery.The impact of PCI on short-term prognosis in patients.Results: There was no significant difference in the incidence of angina pectoris,arrhythmia,heart failure,all-cause death,MACE and adverse events between the two groups during hospitalization(P>0.05).The left ventricular ejection fraction(LVEF)(%)was compared 6 months after surgery: the short-term vs long-term group(56.20±8.95vs49.44±11.08,P=0.002),the difference was statistically significant.The incidence of MACE was 6 months after surgery in the short-term vs long-term group(6.12%vs22.22%,P=0.026),and the difference was statistically significant.The rest included left ventricular end diastolic dimension(LVEDD),and the incidence of angina pectoris and all-cause death were not statistically significant between the late group and the long-term group(P>0.05).Conclusion: For STEMI patients who missed primary PCI,the choice of delayed PCI treatment time did not affect the incidence of in-hospital MACE and adverse events.Patients with STEMI who underwent delayed PCI within 14 days had better cardiac function and short-term prognosis than patients who underwent delayed PCI for more than 14 days.