| ObjectiveUpper respiratory tract infection(URI)is associated with increased incidence of perioperative complications in children undergoing open heart surgery,surgery is often postponed.However,whether the therapeutic cardiac catheterization of children with recent(within two weeks)URI need to be postponed is still unknown.Our study aimed to explore the effect of recent URI on perioperative respiratory adverse events(PRAEs)of congenital heart disease(CHD)children undergoing elective general anesthesia therapeutic cardiac catheterization,and the effect of premedication with intranasal dexmedetomidine.MethodsWe prospectively included children who had general anaesthesia for therapeutic cardiac catheterization,medical history,including recent URI of children was recorded by a questionnaire.The incidence of PRAEs(laryngospasm,bronchospasm,breath holding,oxygen saturation <95%,cough,or glossoptosis)and postoperative dysphoria,fever,copious sputum,or vomiting 24 hours after operation were observed and recorded.Then,children with recent URI were randomly assigned,the effect of intranasal dexmedetomidine on the incidence of PRAEs was observed.ResultsThe overall incidence of PRAEs in children with recent URI increased by 34%,the incidence of laryngospasm,breath holding,SpO2<95%,and cough increased by 4.6%,4.2%,21.1% and 22.2% respectively;recent URI significantly increased the incidence of postoperative copious sputum and dysphoria;but had no effects on hospital lengths of stay.Premedication with intranasal dexmedetomidine reduced the overall incidence of PRAEs by 21.6%.ConclusionsRecent URI significently increased the incidence of perioperative complications in CHD children undergoing elective therapeutic cardiac catheterization,but had no effects on children’s hospital lengths of stay.Premedication with intranasal dexmedetomidine could reduced the incidence of above adverse events effectively. |
