Clinical Study Of Cognitive And Repatency Of Patients With Carotid Artery Stenosis After Stent Implantation Surgury

Objective: To study the cognitive and re flow of patients with carotid artery stenosis stent implantation.Methods: 135 patients with atherosclerotic stenosis of the internal carotid artery and with carotid artery stenosis?70% from Jan.2017 to Jan.2018 in our hospital were selected.The selected patients were randomly divided into two groups: Carotid artery stent implantation treatment group(referred to as Stent group)and drug treatment group(referred to as Drug group).Stent group contained 75 cases,while Drug group contained 60 cases.Cognitive function,clinical efficacy and patency of patients with different treatment methods before and after treatment were statistically analyzed.Results:1.There were no significant differences in MMSE score(Mini-mental State examination,MMSE),MoCA score(Montreal Cognitive Assessment,MoCA),FTT score(Finger Tapping Test,FTT)?WAMS score(Wechsler adult memory scale,WAMS)time required for TMT-A(Trail Making Test A,TMT-A)and TMT-B between the two groups(P>0.05).After treatment,the scores of MMSE,MoCA,FTT,WAMS and time required for TMT-A and TMT-B in stent group were significantly higher than those in drug treatment group.However,after treatment,the MMSE score,MoCA score,FTT score,WAMS score,time required for TMT-A and TMT-B of patients with stent implantation in Stent groups were significantly higher than the patients with drug treatment(P<0.05).In addition,MMSE,MoCA,FTT,WAMS scores in stent group were significantly higher than those in drug group at 1,3 and 6 months after treatment,the time required for TMT-A and TMT-B was significantly shorter than that of drug treatment group(P < 0.05)..2.The MMSE score,MoCA score,FTT score,WAMS score,time required for TMT-A and TMT-B in stent group were significantly different after one month,while those in drug group were significantly different after three months.3.In the stent group,the incidence of carotid TIA and new cerebral infarction was 0% and 4.00% in 75 patients within 6 months after treatment,while in the drug group,the incidence of carotid TIA and new cerebral infarction was 16.7% and 36.67% in 60 patients within 6 months,respectively.Statistical analysis showed that the incidence of carotid TIA and new cerebral infarction in the drug group was significantly higher than that in the stent group(P<0.05).4.Among the 75 cases of patients treated with surgery,51 cases were excellent,15 cases were good,6 cases were better,the total effective rate was 96.0%(72/75);Among the 60 cases of patients treated with drug treatment,30 cases were excellent,9 cases were good,3 cases were better,the total effective rate was 70.0%(42/60).The total effective rate of the surgical treatment was significantly higher than the drug treatment(P<0.05).5.The degree of carotid artery stenosis in stent group decreased from(82.43±8.28)% to(5.76±4.78)%.The difference was significant(P < 0.05).In drug group,the degree of carotid artery stenosis decreased from(83.28±10.52)% to(80.47±9.58)%.The difference was not significant(P > 0.05).Conclusion: This research showed there was a significant positive correlation between the severity of carotid stenosis and the degree of cognitive impairment.And carotid artery stent implantation can significantly improve the cognitive function and carotid artery repatency of patients.Therefore,early intervention should be given to patients with carotid artery stenosis to effectively improve the prognosis of patients.