The Best Optimal Timing Of Laparoscopic Cholecystectomy In Mild Acute Gallstone Pancreatitis

Objective:To invcstigate the best optimal timing of laparoscopic cholecystectomy in mild acute gallstone pancreatitis.Methods:Totally 150 cases of mild acute biliary pancreatitis(MABP)admitted at First Hospital Of ShanXi Medical University from January 1 st 2016 to June 30th 2018 were enrolled.All cases were undergoing laparoscopic cholecystectomy(LC),according to the onset to operation time,the patients were divided into three groups random,group A is Emergency operation team(<72h,n=10),group B is Early operation team(72h—<2weeks,n=50)and group C is Deferred operation team(>2weeks,n=90).Intraoperative blood loss volume,operation time,hospital stay time,medical expense,biochemical indexes such as levels of alanine aminotransferase(ALT),aspartate aminotransferase(AST)and total bilirubin(TBIL)before and 3d after operation,the incidences of postoperative complications(pseudocyst and pancreatic abscess)and recovery and recurrence of pan creatitis were analyzed.Results:Group C had the longest hospital stay and the most expensive medical expense,and Group A had the shortest hospital and the minimum medical expense,(P<0.05),Levels of ALT,AST,TBIL,amylase,lipase,blood glucose and heameba 3 d after operation were significantly lower than tho se before operation;Level of blood calcium was higher than before(P<0.05),there were signiflcant differences of levels of ALT-AST 3d after operation among groups(P<0.05),there wete no significant differences of other biochemical indexes level among groups(P>0.05).There were no significant differences of the incidences of postoperative complications and recarrence rate arnongConclusiontMild biiary AP patients should be operated within 72 h after onset.