Correlation Between Serum 25-hydroxyvitamin D And Parathyroid Hormone Levels And Hypertension In Patients With Type 2 Diabetes

Objective:Whether serum 25-hydroxyvitamin D(VitD)and parathyroid hormone(PTH)are directly related to hypertension in diabetic patients is inconclusive.The article aims to explore the relationship between the three.Methods:A retrospective analysis of 128 patients with type 2 diabetes in the Department of Endocrinology,Second Clinical Hospital of Shanxi Medical Medical University,was divided into two groups according to the presence of hypertension.they were divided into hypertension group(89 cases)and non-hypertension group(39 cases).General information,serum PTH,25-(OH)VitD levels and other data were collected to analyze the relationship between 25-(OH)VitD,PTH and hypertension in diabetic patients.Results:Serum 25-(OH)VitD level of diabetic patients in hypertension group was lower than that in non-hypertension group(11.40 ± 6.71 ? g/L vs 17.32 ± 9.68 ? g/L,P<0.001).Difference in PTH of the two groups lacked statistical significance(42.40 ±22.60 ng/L vs 36.37±15.50 ng/L,P = 0.132).Pearson correlation analysis showed that25-(OH)VitD was negatively correlated with PTH(r=-0.182,P<0.05).Binary Logistic regression indicated that vitamin D deficiency was the independent risk factor of hypertension(OR=0.935,95% CI 0.883-0.991,P=0.023<0.05),whereas PTH showed nocorrelation with hypertension In diabetic patients.Conclusion:Diabetic patients are prone to decrease with 25-(OH)VitD,and 25-(OH)VitD reduction is a risk factor for hypertension in diabetic patients.There was no correlation between PTH and the increased risk of hypertension in patients with type 2 diabetes mellitus.