| Part ?:Objective:To investigate the influence of clinical characteristics on the prognosis of pancreatic cancer.Methods :54 patients with pancreatic cancer were collected from January 2017 to December 2018.The clinical follow-up information including name,sex,diabetes mellitus,tumor stage,lymph node metastasis,vascular invasion,tumor markers,surgical methods and survival time were collected.All data were analyzed by Kaplan-Meier to draw survival curve,and single-factor and multi-factor Cox regression analysis was used to analyze the impact of clinical and pathological characteristics on survival time of patients.Results: COX regression analysis showed that there was no significant correlation between the prognosis of pancreatic cancer patients and their gender,age and whether they underwent extended surgery(P > 0.05),but whether they were accompanied by diabetes mellitus,tumor stage,lymphatic metastasis,vascular invasion,and tumor markers was significant for the prognosis of pancreatic cancer patients(P < 0.05).Conclusions: Tumor staging,lymphatic metastasis,vascular invasion,tumor markers and diabetes mellitus are independent risk factors for the prognosis of pancreatic cancer patients.Part ?:Objective: To investigate the expression level and difference of CECR7 in diabetic-related pancreatic cancer and non-diabetic-related pancreatic cancer.Methods:Fifty patients with pancreatic cancer were collected from November 2017 to January 2019.The expression of CECR7 in diabetes-related pancreatic cancer and non-diabetes-related pancreatic cancer was detected by q RT-PCR.The difference of CECR7 expression between the two groups was analyzed.Results: The expression level of CECR7 in diabetes-related pancreatic cancer was significantly different from that in non-diabetes-related pancreatic cancer,and it was low in diabetes-related pancreatic cancer and high in non-diabetes-related pancreatic cancer(P < 0.05).Conclusions: The expression level of CECR7 in diabetic-related pancreatic cancer is significantly different from that in non-diabetic-related pancreatic cancer. |
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