| Objectives To explore the relationship between body mass index,lipid metabolism and frailty in elderly hypertensive hospitalized patients,so as to improve the patient's frailty state and achieve better blood pressure control.Methods A total of 47 elderly patients diagnosed with hypertension and frailty diagnosed in the Department of Geriatrics of North China University of Technology from November 2017 to May 2018 were enrolled as a case group.106 elderly patients with hypertension and no frailty disease were selected as the control group.Data were collected from all selected elderly hypertensive hospitalized patients,the general clinical data of the patients were recorded,blood samples of hospitalized patients were collected,and blood lipid indexes were measured.The blood lipid indexes included total cholesterol(TC),triglyceride(TG),and high.Density lipoprotein cholesterol(HDL-C),low-density lipoprotein cholesterol(LDL-C),and the like.A clinical database was established,and the data were analyzed by SPSS21.0 software.The measurement data is represented by((?)ąs),the t test is used for comparison between groups;the count datperformed by x2 test.Logistic regression model was used to analyze the risk factors of frailty inpatients with hypertension in the elderly.The difference was statistically significant at p<0.05.Results 1 There were no significant differences in gender,ethnicity,smoking history,drinking history,cerebrovascular disease,admission diastolic blood pressure,and hypertension between the two groups(P>0.05).There were significant differences in age,years of education,multiple medications,duration of hypertension,type 2 diabetes,and coronary heart disease between the two groups(P<0.05).2 There was a statistically significant difference in BMI between the two groups(P<0.05).The risk of wasting in the case group was 9.6 times higher than that in the control group.The risk of overweight in the case group was 2.5 times that in the control group.The risk of obesity in the case group occurred.The sex was 8 times that of the control group.3 There was no significant difference in LDL-C,TC,TG between the two groups(P>0.05).There was a statistically significant difference in HDL-C between the two groups(P<0.05).The elderly patients with hypertension who had increased HDL-C were frailty.The risk is reduced.4 Taking the frailty condition as the dependent variable,the above statistically significant indicators:age,type 2 diabetes,coronary heart disease,years of education,systolic blood pressure,multiple medication,BMI,HDL-C as independent variables,included in the logistic regression model For analysis,there were statistically significant indicators: age(OR=1.363,1.134 to 1.639 95% CI,P<0.05),duration of hypertension(OR=14.202,2.622-7.922 95% CI,P<0.05),type 2 diabetes(OR=5.781,1.054 ~ 31.725 95% CI,P<0.05),multiple doses(OR=15.016,2.762 ~ 81.647 95% CI,P<0.05),HDL-C(OR=0.055,0.004~0.728 95% CI,P<0.05),wasting(OR=38.489,3.212~461.215 95% CI,P<0.05)Obesity(OR=37.287,3.411 to 407.597 95% CI,P<0.05).Conclusions 1 BMI is associated with frailty,and the risk of frailty elderly patients with weight loss and obesity increases.2 HDL-C is associated with frailty,and the risk of frailty hospitalized patients with increased hypertension in HDL-C is reduced.Figure0;Table11;Reference 153... |
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