Epidemiological Analysis Of 3311 Hospitalized Children With Tuberculosis

Objective:Based on the data of children hospitalized with tuberculosis in children's hospital affiliated to Chongqing medical university,the epidemiological trends and characteristics were analyzed to provide data support for further diagnosis,treatment and management of pediatric tuberculosis.Methods :A retrospective analysis was conducted on the hospitalization time,household registration source,gender,age,diagnostic classification and other data information of 3311 tuberculosis children hospitalized in children's hospital affiliated to Chongqing medical university from January 2008 to December 2018.Results:The total number of hospitalized children with tuberculosis was 287 in 2008 and 347 in 2018.The number of pediatric patients from rural sources decreased from 176/287(61.32%)in 2008 to 182/347(50.56%)in 2018.At the same time,the number of pediatric patients with household registration in Chongqing dropped from 181/287(63.07%)in 2008 to 145/347(41.79%)in 2018.The number of male children in 1939/3311(58.56%)was significantly higher than that of female children in 1372/3311(41.44%),and the age of male patients was smaller than that of female patients(P<0.05).The number of hospitalized patients in spring and summer was significantly higher than that in autumn and winter(P<0.05).The age group of 10-17 years old in each year was larger than other groups;Classification of tuberculosis: 2254/3311 cases(68.08%)of pulmonary involvement and 1135/3311 cases(34.28%)of tuberculous meningitis were the main types of extrapulmonary tuberculosis.Tuberculous meningitis is more common in the 0-5 year old range;Abdominal tuberculosis is most common in 5-17 years old;Bone and joint tuberculosis is more common in 1 to <10 years old;Tuberculosis of the genitourinary system is more common in 10-17 years old;The proportion of severe tuberculosis in our hospital was high(41.14%),and it was more common in children aged 0-1 years.The incidence of severe tuberculosis in rural children(45.75%)was higher than that in urban/urban children(35.42%).The incidence of severe tuberculosis in female children(43.89%)was higher than that in male(39.18%).Conclusion:The situation of tuberculosis in children is still severe,and the overall trend is on the rise,while the proportion in rural areas decreases but the trend is urban/urbanization.The lung is still the most easily involved part of tuberculosis,and extrapulmonary tuberculosis is dominated by tuberculous meningitis.The number and proportion of elder children with tuberculosis are high.Young children tuberculosis disease is serious,affected place is much.