The Application Value Of Whole Body Low-dose CT In The Diagnosis And Staging Of Multiple Myeloma

Objective:To investigate the clinical value of whole-body low-dose CT(WBLDCT)in the diagnosis and staging of multiple myeloma(MM).Methods:The imaging data of 58 patients with multiple myeloma confirmed by clinical pathology in our hospital were collected.All the patients were examined with low dose CT,X-ray and whole-body bone imaging.The distribution of bone lesions in low dose CT was compared with X-ray and bone imaging,and the detection rate was compared with the other two modalities At the same time,according to the Durie/Salmon plus staging system and the ISS staging system,and the consistency between them was compared.Results:There was a significant difference in the distribution of bone damage between low-dose CT examination,X-ray examination and bone imaging(all P<0.001),and the detection rate was significantly higher than that of X-ray examination(P<0.001),and there was no significant difference between low-dose CT examination and bone imaging(P>0.05).X-ray examination showed that the main sites were rib and flat bone,limb bone,spine and skull had a lower proportion of damage;The main lesions of the whole body-low-dose CT examination were the spine and ribs,while the proportion of flat bone,limb bone and skull injury was low;The main bone lesions of the bone imaging examination were ribs,followed by the spine,while the pelvis,limb bone,skull,sternum,scapula and clavicle showed a lower proportion of damage;the consistency of whole-body low-dose CT and X-ray examination was “very low”,the consistency of whole-body low-dose CT and systemic bone imaging was “moderate”,and the Durie/Salmon plus staging and the clinical ISS staging had“moderate”consistency.Conclusion:1 Whole-body low-dose CT scan can better evaluate bone damage than X-ray and bone imaging.It is expected to replace traditional X-ray and become the preferred imaging tool for MM screening.2 Whole-body low-dose CT scan can better evaluate MM staging,and provide some help for the choice of MM treatment plan.