| Objective The aim of this study is to provide a preliminary investigation on whether a mirror neurons training cognitive system application can be used to treat VCIND and to identify the combination role of two treatment(r TMS+MNST)in the repair of cognition.Methods Two groups,one of r TMS+MNST group(n = 17)and one of r TMS group(n = 16)were recruited randomly for VCIND from Zhongnan Hospital of Wuhan University.Both groups were given r TMS using the CCY-I.The r TMS+MNST group was additionally given mirror neurons training and patients were provided with a tablet PC for cognitive training exercise.The Montreal cognitive assessment,the mini-mental state examination,the event-related potential 300 and the modified Barthel Index of both groups were measured at baseline and 4 weeks after treatment.Results Before the treatment,no significant differences were found in any of the measurements(P>0.05).At the 4th week after treatment,the average Mo CA,MMSE and P300 consequence showed different degrees of cognitive improvement in each group.The scores of activities of daily living in r TMS+MNST group was higher than that in r TMS group(P<0.05);By longitudinal comparison,the difference of cognitive function in the two groups at the baseline and fourth weeks were statistically significant(P<0.05).Conclusion MNS training system combined with r TMS is more effective than r TMS alone in improving cognition and ADL performance and is worthy of more clinical application and promotion. |
