| Objective The thrombus of location,extent and collateral circulation are important factors influencing the clinical prognosis of patients with ischemic stroke.This article will explore the relationship between the location and extent of thrombus and collateral circulation in patient with Acute Middle Cerebral Artery Infarct.Method CTA was performed in patient with Acute Middle Cerebral Artery Infarct within 72 hours after onset.CTA was used for assessment within 3 days after admission.Flow diversion was assess by TCD 24 hours after admission.According to the different CBS scores of patients,they were divided into two groups(CBS≤6 points CBS>6 points),which were divided into FD+ group and FD-group according to whether flow diversion.Presenting National Institutes of Health Stroke Scale(pre-NIHSS)and 14-day follow-up National Institutes of Health Stroke Scale,3-month follow-up modified Rankin Scale(mRS)scores and general status(gender,age,hypertension,diabetes,coronary heart disease)were the minimum clinical data required for the study.Result A total of 85 patients(mean age,68.5±5.36 years).with acute middle cerebral artery infarction were included in this trial.There were 49 males(58%)and 36 female(42%).The mean NIHSS score was(15.58±4.31).The relationship between CBS and FD was as follows: There are 23(57.5%)of people has CBS > 6 and FD+ vs 17(42.5%)of people has CBS < 6 and FD +.There was significant difference between the two groups(P < 0.01).CBS combined with FD in predicting the prognosis: in patients with mild thrombotic load(CBS > 6),and in the presence of FD,the prognosis of the patients with good neurological function(mRS ≤ 3 months)was the best,the neurological function defect was mild and the infarct size was small(P < 0 05).It was found that the sensitivity of CBS and FD to prognostic outcome was 78%,CBS and FD to prognostic outcome was 61% and 77.5%,respectively.There was no significance difference in the three group.Conclusion In patients with acute middle cerebral artery infarction(MCA),the neurological function was better in patients with TCD-FD and mild thrombus load.FD was higher in patients with smaller thrombus extent.Also,CBS combined with FD is not superior to the CBS or FD in evaluating the prognosis. |
