The Analysis Of The Related Factors And TCM Syndrome Of Postoperative Recurrence Of Kidney Stone

Purpose:Through the retrospective collection of the patients with kidney stones,the possible relationship between the postoperative recurrence and the syndrome of the traditional Chinese medicine and the related factors is summarized,and the thought for preventing the recurrence of the kidney stones is provided for the dialectical treatment of the traditional Chinese medicine.Method:Retrospective collection of patients hospitalized for nephrolithiasis from October 2014 to October 2016,with the inclusion of criteria and exclusion criteria to select the patients required to meet the requirements of the study.The time of the review was 2 years.The recurrence of the kidney stones in 2 years was the case group,and no recurrence of the kidney stones in the 2 years was the control group.Collect relevant information of qualified patients,including gender,age,long axis of kidney stone,whether double-sided kidney stones,staghorn kidney stones,hyperuricemia,serum high blood calcium,and syndrome differentiation of Chinese medicine.The obtained information was built into the relevant database.The data analysis method was carried out by the statistical analysis software.The card-side test or the FISHER-exact method was used for single factor analysis,and the multivariate logistic regression analysis was selected for binary logistic regression analysis(P<0.05 was the statistical significance value).Results:In this study,there were 129 patients with satisfactory results,including 15 of the cases and 114 in the control group.The recurrence rate was 11.63%.There were 81 cases of male and 48 cases of female patients,10 cases of recurrence and 5 cases of recurrence respectively.The minimum age was 18 years,the maximum age was 73 years,the average age was 52.66±10.82,There were severally 26 cases,66 cases,37 cases in the 18～44 age group,the 45～59 age group,the 60～74 age group,3 cases,8 cases and 4 cases of recurrence respectively.The minimum length of the long axis of the kidney stone was 0.9cm,the maximum was 7.2cm,and the average length of stone axis was 2.71±1.32 cm.There were 53 cases,42 cases and 34 cases in 2cm group,2～3cm group and>3cm group respectively.There were 1 case,8 cases and 6 cases of postoperative recurrence respectively in the group of stone long axis<2cm,group 2～3cm and group>3cm.There were 87 cases of the unilateral kidney stone and 42 cases of the bilateral kidney stone,6 cases of recurrence and 9 cases of recurrence respectively.There were 37 cases of staghorn kidney stone and 92 cases of non-staghorn kidney stone,10 cases of recurrence and 5 cases of recurrence respectively.There were 50 cases of hyperuricemia and 79 cases of non-hyperuricemia,9 cases of postoperative recurrence and 6 cases of postoperative recurrence respectively.There were 7 cases of hyperuricemia and 122 cases of non-serum hyperuricemia,2 cases of postoperative recurrence and 13 cases of postoperative recurrence respectively.In the distribution of syndromes,damp-heat accumulation syndrome was the most common type of calculus.In 129 cases,13 cases were damp-heat accumulation syndrome,which accounted for 86.67 points,while Qi and blood stagnation syndrome and kidney qi deficiency syndrome had only 1 case each,accounting for 6.67%respectively.In the control group,there were 47 cases of damp-heat accumulation syndrome(41.23),33 cases of Qi and blood stasis syndrome(28.95%)and 34 cases of kidney qi deficiency syndrome(29.82%).Univariate analysis showed that there was no significant difference in sex,age,hyperuricemia and serum calcium levels in the recurrence of renal calculi,but whether there were bilateral kidney stones and staghorn kidney stones have statistical significance.Besides,there was significant difference in the size of long axis of renal calculi and the type of litholithiasis in traditional Chinese medicine,and there was significant difference between the 2cm group and 2～3cm group and>3cm group,but there was no significant difference between 2～3cm group and>3cm group.There were significant differences between damp-heat accumulation type and Qi and blood stasis type and kidney Qi deficiency type in TCM syndrome type,but there was no statistical significance between Qi and Blood stasis type and Kidney Qi deficiency type.The results of binary logistic regression analysis showed that bilateral renal calculi,staghorn nephrolithiasis and damp-heat accumulation were the risk factors for the recurrence of renal calculi,and the recurrence of bilateral renal calculi was 7.78 times as high as that of unilateral renal calculi.The postoperative recurrence of staghorn nephrolithiasis was 5.196 times of that of non-staghorn nephrolithiasis and the postoperative recurrence of damp-heat accumulation nephrolithiasis was 11.168 times as high as that of non-dampness-heat-accumulation nephrolithiasis.Conclusion:1、The recurrence rate of kidney stone was high,and the recurrence rate in 2 years was 11.63%.2、Sex,age,hyperuricemia and serum calcium levels were not correlated with kidney stone recurrence.3、In TCM syndrome differentiation,damp-heat accumulation type is the most common type,and damp-heat accumulation type is the risk factor of kidney stone recurrence,the postoperative recurrence of damp-heat accumulation type kidney stone was 11.168 times as high as that of non-damp-heat accumulation type kidney stone.4、Bilateral kidney stone and staghorn kidney stone are risk factors for the recurrence of kidney stone.The postoperative recurrence of bilateral kidney stone was 7.78 times of that of unilateral kidney stone and the postoperative recurrence of staghorn nephrolithiasis was 5.196 times as high as that of non-staghorn nephrolithiasis.