| ObjectiveBy analyzing the medical records and the results of auxiliary examinations of inpatients who had previously received diabetic foot treatment,the TCM and clinical characteristics of patients with diabetic foot with different prognosis were analyzed,and the abnormalities of biochemical indicators were analyzed,which might indicate the high risk of amputation(toe).Therefore,according to the results of the study,diabetic foot patients with high risk of amputation(toe)could be treated clinically.Early prevention and treatment can delay the progress of the disease and improve the prognosis.MethodsA retrospective analysis was made of the diabetic foot patients treated in the Department of Endocrinology,Foshan Hospital of Traditional Chinese Medicine from 2013 to 2017.The patients were grouped according to different prognosis,and related data such as hospitalization records,test results were collected,summarized and counted.For patients who had been hospitalized for many times,the data of each hospitalization were included in the prognostic grouping.The purpose of this study is to compare the differences of TCM and clinical characteristics of diabetic foot patients with different prognosis,and to analyze which abnormal indicators may indicate a high risk of amputation(toe).The main contents of the analysis include:the general characteristics of diabetic foot patients with different prognosis,characteristics of traditional Chinese medicine,test and inspection indicators,etc.Results1.There was no significant difference in sex ratio and age between amputation(toe)group and non-amputation(toe)group(P>0.05).2.Distribution of TCM syndromes in patients with diabetic foot:286 cases(56.1%)with Yin deficiency and toxic excess,89 cases(17.5%)with blood stasis,46 cases(9.0%)with Yang cold and blood stasis,and 89 cases(17.5%)with Qi and blood deficiency.3.There was no significant difference in the course of diabetes between amputated(toe)group and non-amputated(toe)group(P>0.05),but there was no significant difference in the course of diabetic foot(P>0.05).4.There were significant differences between amputation(toe)group and non-amputation(toe)group in hypertension,lower extremity arteriosclerosis occlusion,heart and kidney insufficiency(P<0.05).There was no significant difference between amputation(toe)group and non-amputation(toe)group in coronary heart disease and cerebral infarction(P>0.05).5.The Wagner grading distribution of amputated(toe)group and non-amputated(toe)group was compared.There was significant difference in Wagner grading distribution between the two groups(P<0.05).6.There was no significant difference in pathogenic bacteria composition between amputated(toe)group and non-amputated(toe)group(P>0.05).7.The biochemical indexes of amputated(toe)group and non-amputated(toe)group were compared:there was no significant difference in random blood sugar level between the two groups(P>0.05);there was significant difference in glycosylated hemoglobin level between the two groups(P<0.05);there was no significant difference in C-peptide level between the two groups(P>0.05);there was no significant difference in insulin level between the two groups(P>0.05);There were significant differences in interleukocyte count(P<0.05),hemoglobin count(P<0.05),platelet count(P<0.05),albumin level(P<0.05),total cholesterol level(TC)between the two groups(P<0.05).There were significant differences between the two groups(P<0.05),low density lipoprotein(LDL)level between the two groups(P<0.05),high density lipoprotein(HDL)level between the two groups(P<0.05),and serum creatinine level between the two groups(P>0.05).ConclusionAccording to the analysis of this study,the majority of diabetic foot inpatients in Endocrinology Department of Foshan Hospital of Traditional Chinese Medicine are elderly people,and more males than females.The main type of syndrome differentiation of traditional Chinese medicine is Yin deficiency and toxic excess.Wagner grade of diabetic foot inpatients is Wagner grade 2,and Wagner grade 4 is the main type of amputation patients.The results showed that Wagner grade,blood glucose and lipid level,white blood cell count,hemoglobin,platelet count,albumin level,hypertension,arteriosclerosis obliteration of lower extremities,and biochemical indexes of patients with different prognosis were statistically analyzed.The results showed that Wagner grade,blood sugar and lipid level,white blood cell count,hemoglobin,platelet count,albumin level,hypertension,arteriosclerosis obl iteration of lower extremities,and so on.There were significant differences in the proportion of heart and kidney insufficiency between amputation group and non-amputation group,suggesting that diabetic foot patients with high Wagner grade,poor control of blood sugar and lipid,poor control of infection,high blood viscosity,poor nutritional status,hypertension,arteriosclerosis obliteration of lower extremities,heart and kidney insufficiency had higher amputation(toes)Risk. |
