Comparison Of Clinical Efficacy Between Single-hole And Multi-hole Thoracoscopic Segmentectomy For Early Stage Non-small Cell Lung Cancer

OBJECTIVES A retrospective study was carried out on lung cancer patients undergoing VATS segmentectomy,with the aim of determining whether uniport video-assisted seg-mentectomy has more favorable postoperative outcomes than multiport VATS seg-mentectomy techniques(Two-port and three-port VATS).METHODSPatients were assigned to two groups;uniport video-assisted segmentectomy(Group I;n=142)and multiport VATS segmentectomy(Group ?;n=361).The primary outcome measures were:disease free survival;the secondary outcome measures were:the number and location of lymph nodes harvested,intraoperative blood loss,operation time,the duration of the postoperative hospital stay.Quantity of drain,postoperative complications in 30 days.RESULTS The number of lymph nodes(P=0.34),postoperative hospital stay(P=0.90),an d postoperative drainage tube time(P=0.90)were not statistically significant in the two g roups.Hospitalization expenses(P<0.01),operation time(P<0.01),intraoperative blood loss(P=0.01),postoperative drainage volume(P<0.01),there were differences between t he two groups,in the median and interquartile range analysis,the values of operation tim e,intraoperative blood loss,and postoperative drainage volume in group 2 was higher tha n group 1,as to hospitalization expenses,group 1 was higher than group 2.Log-rank anal ysis was used in 428 follow-up patients to find no significant difference in the cumulative recurrence rate between patients undergoing single-thoracic thoracoscopic segmentecto my and patients undergoing massive thoracoscopic segmentectomy(P=0.417).Also,in s ubsequent subgroup analyses,there was no statistically significant difference in cumulati ve recurrence rates between patients who underwent thoracoscopic segmental resection a nd patients who were 2 cm or less and those who were greater than 2 cm and less than or equal to 3 cm(P=0.316)CONCLUSIONSingle-hole thoracoscopic rather than porous thoracoscopic surgery is completely safe and feasible in patients with non-small cell early lung cancer who have been carefully screened for appropriate segmental resection.