Clinical Observation On Treatment Of Climacteric Insomnia With Stagnation Of Liver Qi By Adding And Reducing Chaihu Jiaolong Bone Oyster Soup

Objective:To observe the efficacy of adding and minus Chaihu and Keel oyster decoction in the treatment of menopausal insomnia(liver gas depression type),to explore the effectiveness of adding and minus Chaihu and keel oyster decoction to the treatment of menopausal insomnia,and to evaluate its safety,and to provide effective basis for the popularization of its further clinical application.Methods:In this study,60 patients from the Department of Rehabilitation Clinic of Shanxi University of Traditional Chinese Medicine and the Neurology Clinic of Shanxi Grand Hospital were collected from January 2018 to November 2018,which were randomly divided into treatment group and control group in 30 cases,the treatment group was given to add and subtract chaihu and keel oyster soup,and the control group was given oral alprazolam tablets.Both groups of patients were revisit once a week.The changes of curative effect observation index were recorded before treatment,1 weeks treatment,2 weeks treatment and 2 weeks after withdrawal,and the data analysis was carried out by using SPSS20.0 statistical software.Results:1.In terms of age and disease course,there was no significant difference between the two groups(P>0.05),which was comparable.2.Before treatment,there was no significant difference between the treatment group and the control group in TCM syndrome scale score,Pittsburgh sleep index scale score and modified kupperman score(P>0.05),which was comparable.3.Compared with 1 weeks before treatment,The scores of TCM syndrome scale and modified kupperman in the treatment group were significantly lower than those in the control group(P<0.05),and the scores of Pittsburgh sleep index scale in the control group were significantly lower than those in the treatment group(P<0.05).4.2 weeks of treatment and 1 weeks of treatment,The scores of TCM syndrome scale and modified kupperman in the treatment group were significantly lower than those in the control group(P<0.05),and the scores of Pittsburgh sleep index scale in the treatment group were not significantly different from those in the control group(P>0.05).5.2 weeks of treatment and 2 weeks of withdrawal,2 weeks of withdrawal and comparison before treatment,The scores of TCM syndrome scale,Pittsburgh sleep index scale and modified kupperman in the treatment group were all significantly lower than those in the control group(P<0.05).6.Safety observation:during the treatment,no adverse reactions occurred in the two groups.Conclusion:The treatment of menopausal insomnia with the addition of Chaihu and Keel Oyster decoction has an exact therapeutic effect,and has no toxic side effects,and has a good prospect of development,which is worthy of clinical application.