Objective: To evaluate the clinical efficacy and safety of the Modified Banxia Baizhu Tianma Decoction by the clinical observation of the application of Modified Banxia Baizhu Tianma Decoction in the treatment of residual dizziness after benign paroxysmal positional vertigo reduction.Method:60 patients who were diagnosed as benign paroxysmal positional vertigo in the Department of Encephalopathy of Hubei Provincial Hospital of Traditional Chinese Medicine(Garden Mountain Hospital District)and operated by the successful canalith repositioning maneuvers but the residual dizziness still exists during the period from January 2017 to June2018,were included in the study.The 60 patients were divided into the experience group and the control group according to the random principle.Each group contains 30 patients.There were no statistical differences in gender,age distribution and concomitant diseases(P>0.05).The experience group was treated with modified Banxia Baizhu Tianma Decoction(pinellia 10 g,Tianma10g,Baizhu 10 g,Poria cocos 15 g,tangerine peel 10 g,astragalus membranaceus 15 g,rhizoma alisma 10 g,,angelica 10 g,Chuanxiong 10 g,licorice 6g,ginger 10 g,jujube 10g),200 ml of boiling water decoction,Taking100 ml in the morning and 100 ml in the evening;the control group was givenbetahistine mesylate tablets [specification: 6mg,national medicine standard:H20040130,Eisai(China)Pharmaceutical Co.,Ltd.] orally,3 times a day,6mg each time for 2 weeks.The Dizziness Handicap Inventory(DHI),the Visuo-Analogic Scale(VAS),and the Dizziness Clinical Symptom Score Table were evaluated at the beginning of the drug administration and at 2 weeks of treatment,as the two groups of efficacy observation indicators;the general vital signs(blood pressure,respiratory,heart rate,pulse)and electrocardiogram,blood routine,urine routine,stool routine,liver function,and renal function as safety evaluation indicators.Results:(1)The physical score(P),functional score(F),emotional score(E),and total score of the DHI showed that both groups were effective(P<0.05),and the experience group was better(P<0.05).(2)The VAS showed that both treatments were effective in improving subjective dizziness score and dizziness(P<0.05),and the experience group was better(P<0.05);(3)the Dizziness Clinical Symptom Score Table showed that the two groups of treatments were effective in improving the clinical symptoms of patients with TCM(P<0.05),and the texperience group was better(P<0.05).(4)The efficacy of TCM symptoms showed that the effective rate of the experience group was93.3%,and the control group was 73.33%,the difference was statistically significant(P<0.05),and the texperience group was more effective.(5)There were no abnormalities in the safety evaluation indicators during the research,which porves the safety of the Modified Banxia Baizhu Tianma Decoction.Conclusion : The Modified Banxia Baizhu Tianma Decoction for the treatment of benign paroxysmal positional vertigo after successful reduction of residual dizziness has a good clinical effect,and it can significantly improve the residual dizziness symptoms of patients,and it has no adversereactions.The Modified Banxia Baizhu Tianma Decoction has good clinical effect and safety,and it is worthy of popularization and application in clinical practice. |