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Clinical Observation On The Treatment Of Sympathetic Cervical Spondylopathy With Wen Dan Decoction

Posted on:2020-10-30Degree:MasterType:Thesis
Country:ChinaCandidate:L HongFull Text:PDF
GTID:2404330575955664Subject:Fractures of TCM science
Abstract/Summary:PDF Full Text Request
ObjectiveTo compare the clinical effects of Wendan Decoction and nonsteroidal anti-inflammatory drug Celebrex combined with microcirculation expander Sibelin in the treatment of sympathetic cervical spondylosis,which can relieve the symptoms of sympathetic cervical spondylosis,such as headache,dizziness,panic,chest distress,nausea and vomiting,insomnia and anxiety.And to observe the clinical effect of Wendan Decoction in the treatment of sympathetic cervical spondylosis,to explore the clinical substitution effect of Wendan Decoction on nonsteroidal anti-inflammatory drugs and expanding microcirculation drugs.In order to better play the traditional Chinese medicine in the treatment of sympathetic cervical spondylosis clinical advantages.MethodsThe selected clinical observation cases were all from patients in orthopedics and traumatology clinic of Hubei Traditional Chinese Medicine Hospital from November 2017 to November 2018.All patients were carefully inquired about the medical history,physical examination,recording the main clinical symptoms and related complications,such as sleep,diet,urine and feces,emotions,etc.,and collecting the data of the four diagnoses of traditional Chinese medicine and related imaging data.According to the modern medical diagnostic criteria of sympathetic cervical spondylosis,the diagnostic criteria of TCM syndromes and the inclusion and exclusion criteria of cases,a total of 71 patients were screened out.Among them,36 cases were in traditional Chinese medicine group and 35 cases were in western medicine group.The traditional Chinese medicine group was treated with Wendan Decoction for 3 weeks,while the western medicine group was treated with Celebrex and Sibelin for 3 weeks.Finally,we observed and recorded in detail the scores of each observation index,the comprehensive efficacy analysis and the occurrence of clinical side effects(epigastric pain,sleepiness)after 2 weeks and 3 weeks of treatment,and the recurrence of follow-up at the end of 4 months.All the results were compared by statistical methods.ResultsThe general situation and the symptom scores of the two groups before the treatment were compared statistically,and the results showed that P>0.05,there was no significant statistical difference,with comparability.Intragroup Comparison of two groups of patients before and after treatment: the situation of 2 weeks after treatment and 3 weeks after treatment Compared with before treatment,the VAS scores of the two groups decreased,and P<0.01,there were significant differences and statistical significance.It is suggested that both groups can effectively improve the pain of patients after treatment.From typical clinical symptoms,such as headache,dizziness,panic,chest tightness,nausea and vomiting.Compared with before treatment,Chinese medicine group had significant difference in 2 weeks and 3 weeks after treatment,P<0.01,with statistical significance.Western medicine group in 2 weeks after treatment,3 weeks after treatment compared with before treatment,P<0.05,the difference was statistically significant.According to SAS and SRSS scores,there was significant difference between the two groups in 2 weeks and 3 weeks after treatment compared with before treatment(P<0.05).Comparison between two groups after treatment: there was no significant difference in VAS score,head and neck pain and vertigo between the two groups after treatment(P>0.05).There were significant differences in SAS score,SRSS score,nausea,vomiting and chest distress(P<0.05).After treatment,the clinical side effects(stomachache,sleepiness)were 8.33% in the Chinese medicine group and 28.57% in the western medicine group,P<0.05.The difference was statistically significant.In terms of comprehensive curative effect,the comprehensive curative effect of traditional Chinese medicine group was 86.11%,while that of Western medicine group was 82.86%,P>0.05.There was no significant difference between the two groups.Comparisons of recurrence rate between two groups at 4 months follow-up after treatment: at the 4th month,telephone followup showed that there was no significant difference in recurrence between the two groups(P>0.05).ConclusionFor the treatment of sympathetic cervical spondylosis,the dialectical treatment of traditional Chinese medicine is used clinically.Through the analysis of the etiology and pathogenesis of typical symptoms,the treatment principles of warming gallbladder and stomach,regulating qi-flowing for eliminating phlegm,Qingyang Tongmai,are adopted.The application of Wendan Decoction in the treatment of sympathetic cervical spondylosis can improve the pain,typical symptoms such as head and neck pain,vertigo,panic,chest tightness,nausea and vomiting,anxiety and insomnia.It can also effectively reduce the side effects of drugs on the premise of guaranteeing the curative effect.It can replace the non-steroidal anti-inflammatory drug Celebrex and the microcirculation expanding drug Sibelin to improve patients’ satisfaction.It provides a favorable evidence for the idea of replacing modern chemical preparations with traditional herbal medicine and is worthy of further clinical research and application.
Keywords/Search Tags:Sympathetic cervical spondylosis, Bidisease, Wen Dan decoction, celecoxib, Flunarizine hydrochloride
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